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Multiple roles for RhoA during T cell transendothelial migration

T cells need to cross endothelial barriers during immune surveillance and inflammation. This involves T-cell adhesion to the endothelium followed by polarization and crawling with a lamellipodium at the front and contractile uropod at the back. T cells subsequently extend lamellipodia and filopodia...

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Bibliografiske detaljer
Main Authors: Heasman, Sarah J, Ridley, Anne J
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116607/
https://ncbi.nlm.nih.gov/pubmed/21686273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.1.3.14724
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