Coordinated RhoA signaling at the leading edge and uropod is required for T cell transendothelial migration

Transendothelial migration (TEM) is a tightly regulated process whereby leukocytes migrate from the vasculature into tissues. Rho guanosine triphosphatases (GTPases) are implicated in TEM, but the contributions of individual Rho family members are not known. In this study, we use an RNA interference...

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Detalhes bibliográficos
Main Authors: Heasman, Sarah J., Carlin, Leo M., Cox, Susan, Ng, Tony, Ridley, Anne J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2010
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928012/
https://ncbi.nlm.nih.gov/pubmed/20733052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201002067
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