Rac1 links leading edge and uropod events through Rho and myosin activation during chemotaxis

Chemotactic responsiveness is crucial to neutrophil recruitment to sites of infection. During chemotaxis, highly divergent cytoskeletal programs are executed at the leading and trailing edge of motile neutrophils. The Rho family of small GTPases plays a critical role in cell migration, and recent wo...

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Detalhes bibliográficos
Main Authors: Pestonjamasp, Kersi N., Forster, Carol, Sun, Chunxiang, Gardiner, Elisabeth M., Bohl, Ben, Weiner, Orion, Bokoch, Gary M., Glogauer, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: © 2006 by The American Society of Hematology 2006
Assuntos:
Phagocytes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895589/
https://ncbi.nlm.nih.gov/pubmed/16809619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-01-010363
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