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Hem-1 Complexes Are Essential for Rac Activation, Actin Polymerization, and Myosin Regulation during Neutrophil Chemotaxis

Migrating cells need to make different actin assemblies at the cell's leading and trailing edges and to maintain physical separation of signals for these assemblies. This asymmetric control of activities represents one important form of cell polarity. There are significant gaps in our understan...

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Bibliografske podrobnosti
Main Authors: Weiner, Orion D, Rentel, Maike C, Ott, Alex, Brown, Glenn E, Jedrychowski, Mark, Yaffe, Michael B, Gygi, Steven P, Cantley, Lewis C, Bourne, Henry R, Kirschner, Marc W
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1334198/
https://ncbi.nlm.nih.gov/pubmed/16417406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0040038
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