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Human neutrophils coordinate chemotaxis by differential activation of Rac1 and Rac2

Rac1 and Rac2, members of the small Rho GTPase family, play essential roles in coordinating directional migration and superoxide production during neutrophil responses to chemoattractants. While earlier studies in Rac1 and Rac2 knockout mice have demonstrated unique roles for each Rac isoform in che...

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Bibliografische gegevens
Hoofdauteurs: Zhang, Hui, Sun, Chunxiang, Glogauer, Michael, Bokoch, Gary M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056163/
https://ncbi.nlm.nih.gov/pubmed/19625648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900849
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