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mTOR and differential activation of mitochondria orchestrate neutrophil chemotaxis

Neutrophils use chemotaxis to locate invading bacteria. Adenosine triphosphate (ATP) release and autocrine purinergic signaling via P2Y2 receptors at the front and A2a receptors at the back of cells regulate chemotaxis. Here, we examined the intracellular mechanisms that control these opposing signa...

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Publicat a:J Cell Biol
Autors principals: Bao, Yi, Ledderose, Carola, Graf, Amelie F., Brix, Bianca, Birsak, Theresa, Lee, Albert, Zhang, Jingping, Junger, Wolfgang G.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586745/
https://ncbi.nlm.nih.gov/pubmed/26416965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201503066
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