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mTOR and differential activation of mitochondria orchestrate neutrophil chemotaxis

Neutrophils use chemotaxis to locate invading bacteria. Adenosine triphosphate (ATP) release and autocrine purinergic signaling via P2Y2 receptors at the front and A2a receptors at the back of cells regulate chemotaxis. Here, we examined the intracellular mechanisms that control these opposing signa...

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Bibliografske podrobnosti
izdano v:J Cell Biol
Main Authors: Bao, Yi, Ledderose, Carola, Graf, Amelie F., Brix, Bianca, Birsak, Theresa, Lee, Albert, Zhang, Jingping, Junger, Wolfgang G.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586745/
https://ncbi.nlm.nih.gov/pubmed/26416965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201503066
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