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RhoA and RhoC have distinct roles in migration and invasion by acting through different targets

Several studies suggest that RhoA and RhoC, despite their sequence similarity, have different roles in cell migration and invasion, but the molecular basis for this is not known. Using RNAi, we show that RhoA-depleted cells became elongated and extended multiple Rac1-driven narrow protrusions in 2D...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Vega, Francisco M., Fruhwirth, Gilbert, Ng, Tony, Ridley, Anne J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166870/
https://ncbi.nlm.nih.gov/pubmed/21576392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201011038
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