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Coordinated RhoA signaling at the leading edge and uropod is required for T cell transendothelial migration

Transendothelial migration (TEM) is a tightly regulated process whereby leukocytes migrate from the vasculature into tissues. Rho guanosine triphosphatases (GTPases) are implicated in TEM, but the contributions of individual Rho family members are not known. In this study, we use an RNA interference...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Heasman, Sarah J., Carlin, Leo M., Cox, Susan, Ng, Tony, Ridley, Anne J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928012/
https://ncbi.nlm.nih.gov/pubmed/20733052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201002067
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