The Pentose Phosphate Pathway Dynamics in Cancer and Its Dependency on Intracellular pH

The Pentose Phosphate Pathway (PPP) is one of the key metabolic pathways occurring in living cells to produce energy and maintain cellular homeostasis. Cancer cells have higher cytoplasmic utilization of glucose (glycolysis), even in the presence of oxygen; this is known as the “Warburg Effect”. How...

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Publicat a:Metabolites
Autors principals: Alfarouk, Khalid O., Ahmed, Samrein B. M., Elliott, Robert L., Benoit, Amanda, Alqahtani, Saad S., Ibrahim, Muntaser E., Bashir, Adil H. H., Alhoufie, Sari T. S., Elhassan, Gamal O., Wales, Christian C., Schwartz, Laurent H., Ali, Heyam S., Ahmed, Ahmed, Forde, Patrick F., Devesa, Jesus, Cardone, Rosa A., Fais, Stefano, Harguindey, Salvador, Reshkin, Stephan J.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Review
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7407102/
https://ncbi.nlm.nih.gov/pubmed/32664469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/metabo10070285
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