Glycolysis, tumor metabolism, cancer growth and dissemination. A new pH-based etiopathogenic perspective and therapeutic approach to an old cancer question

Cancer cells acquire an unusual glycolytic behavior relative, to a large extent, to their intracellular alkaline pH (pH(i)). This effect is part of the metabolic alterations found in most, if not all, cancer cells to deal with unfavorable conditions, mainly hypoxia and low nutrient supply, in order...

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Detalhes bibliográficos
Publicado no:Oncoscience
Main Authors: Alfarouk, Khalid O., Verduzco, Daniel, Rauch, Cyril, Muddathir, Abdel Khalig, Adil, H. H Bashir, Elhassan, Gamal O., Ibrahim, Muntaser E., David Polo Orozco, Julian, Cardone, Rosa Angela, Reshkin, Stephan J., Harguindey, Salvador
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Perspective
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303887/
https://ncbi.nlm.nih.gov/pubmed/25621294
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