Glycolysis, tumor metabolism, cancer growth and dissemination. A new pH-based etiopathogenic perspective and therapeutic approach to an old cancer question

Cancer cells acquire an unusual glycolytic behavior relative, to a large extent, to their intracellular alkaline pH (pH(i)). This effect is part of the metabolic alterations found in most, if not all, cancer cells to deal with unfavorable conditions, mainly hypoxia and low nutrient supply, in order...

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Bibliographic Details
Published in:Oncoscience
Main Authors: Alfarouk, Khalid O., Verduzco, Daniel, Rauch, Cyril, Muddathir, Abdel Khalig, Adil, H. H Bashir, Elhassan, Gamal O., Ibrahim, Muntaser E., David Polo Orozco, Julian, Cardone, Rosa Angela, Reshkin, Stephan J., Harguindey, Salvador
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2014
Subjects:
Research Perspective
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303887/
https://ncbi.nlm.nih.gov/pubmed/25621294
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