pH-Channeling in Cancer: How pH-Dependence of Cation Channels Shapes Cancer Pathophysiology

Tissue acidosis plays a pivotal role in tumor progression: in particular, interstitial acidosis promotes tumor cell invasion, and is a major contributor to the dysregulation of tumor immunity and tumor stromal cells. The cell membrane and integral membrane proteins commonly act as important sensors...

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Bibliografiske detaljer
Udgivet i:Cancers (Basel)
Main Authors: Pethő, Zoltán, Najder, Karolina, Carvalho, Tiago, McMorrow, Roisin, Todesca, Luca Matteo, Rugi, Micol, Bulk, Etmar, Chan, Alan, Löwik, Clemens W. G. M., Reshkin, Stephan J., Schwab, Albrecht
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7565548/
https://ncbi.nlm.nih.gov/pubmed/32887220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12092484
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