ß1 Integrin Binding Phosphorylates Ezrin at T567 to Activate a Lipid Raft Signalsome Driving Invadopodia Activity and Invasion

Extracellular matrix (ECM) degradation is a critical process in tumor cell invasion and requires matrix degrading protrusions called invadopodia. The Na(+)/H(+) exchanger (NHE1) has recently been shown to be fundamental in the regulation of invadopodia actin cytoskeleton dynamics and activity. Howev...

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Main Authors: Antelmi, Ester, Cardone, Rosa A., Greco, Maria R., Rubino, Rosa, Di Sole, Francesca, Martino, Nicola A., Casavola, Valeria, Carcangiu, MariaLuisa, Moro, Loredana, Reshkin, Stephan J.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3782503/
https://ncbi.nlm.nih.gov/pubmed/24086451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075113
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