Caricamento...

Ezrin regulates focal adhesion and invadopodia dynamics by altering calpain activity to promote breast cancer cell invasion

Up-regulation of the cytoskeleton linker protein ezrin frequently occurs in aggressive cancer types and is closely linked with metastatic progression. However, the underlying molecular mechanisms detailing how ezrin is involved in the invasive and metastatic phenotype remain unclear. Here we report...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Mol Biol Cell
Autori principali: Hoskin, Victoria, Szeto, Alvin, Ghaffari, Abdi, Greer, Peter A., Côté, Graham P., Elliott, Bruce E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2015
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4591691/
https://ncbi.nlm.nih.gov/pubmed/26246600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-12-1584
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !