Curing cancer? Further along the new pH-centric road and paradigm

Por Harguindey, S., Koltai, T., Reshkin, S. J.
Publicado no Oncoscience (2018)

Role of Stromal Cells in Determining Tumor and Cancer Stem Cell Behaviors and Therapeutic Response

Por Reshkin, Stephan J., Cardone, Rosa Angela
Publicado no Cancers (Basel) (2020)

Hydrogen ion dynamics and the Na(+)/H(+) exchanger in cancer angiogenesis and antiangiogenesis

Por Orive, G, Reshkin, S J, Harguindey, S, Pedraz, J L
Publicado em 2003

Synergy Between Low Dose Metronomic Chemotherapy and the pH-Centered Approach Against Cancer

Por Koltai, Tomas, Cardone, Rosa A., Reshkin, Stephan J.
Publicado no Int J Mol Sci (2019)

Metabolic Shifts as the Hallmark of Most Common Diseases: The Quest for the Underlying Unity

Por Schwartz, Laurent, Henry, Marc, Alfarouk, Khalid O., Reshkin, Stephan J., Radman, Miroslav
Publicado no Int J Mol Sci (2021)

Association of pS2 (TFF1) release with breast tumour proliferative rate: in vitro and in vivo studies

Por Potten, Christopher, Darzynkiewicz, Zbigniew, Sasaki, Kohsuke, Reshkin, S. J., Tedone, T., Correale, M., Mangia, A., Casavola, V., Paradiso, A.
Publicado no Cell Prolif (2003)

The Na(+)–H(+ )exchanger-1 induces cytoskeletal changes involving reciprocal RhoA and Rac1 signaling, resulting in motility and invasion in MDA-MB-435 cells

Por Paradiso, Angelo, Cardone, Rosa Angela, Bellizzi, Antonia, Bagorda, Anna, Guerra, Lorenzo, Tommasino, Massimo, Casavola, Valeria, Reshkin, Stephan J
Publicado em 2004

CFTR regulation in human airway epithelial cells requires integrity of the actin cytoskeleton and compartmentalized cAMP and PKA activity

Por Monterisi, Stefania, Favia, Maria, Guerra, Lorenzo, Cardone, Rosa A., Marzulli, Domenico, Reshkin, Stephan J., Casavola, Valeria, Zaccolo, Manuela
Publicado em 2012

Cariporide and other new and powerful NHE1 inhibitors as potentially selective anticancer drugs – an integral molecular/biochemical/metabolic/clinical approach after one hundred ye...

Por Harguindey, Salvador, Arranz, Jose Luis, Polo Orozco, Julian David, Rauch, Cyril, Fais, Stefano, Cardone, Rosa Angela, Reshkin, Stephan J
Publicado em 2013

Protein Kinase A Gating of a Pseudopodial-located RhoA/ROCK/p38/NHE1 Signal Module Regulates Invasion in Breast Cancer Cell Lines

Por Cardone, Rosa A., Bagorda, Anna, Bellizzi, Antonia, Busco, Giovanni, Guerra, Lorenzo, Paradiso, Angelo, Casavola, Valeria, Zaccolo, Manuela, Reshkin, Stephan J.
Publicado em 2005

The NHERF1 PDZ2 Domain Regulates PKA–RhoA–p38-mediated NHE1 Activation and Invasion in Breast Tumor Cells

Por Cardone, Rosa A., Bellizzi, Antonia, Busco, Giovanni, Weinman, Edward J., Dell'Aquila, Maria E., Casavola, Valeria, Azzariti, Amalia, Mangia, Anita, Paradiso, Angelo, Reshkin, Stephan J.
Publicado em 2007

Proton dynamics in cancer

Por Huber, Veronica, De Milito, Angelo, Harguindey, Salvador, Reshkin, Stephan J, Wahl, Miriam L, Rauch, Cyril, Chiesi, Antonio, Pouysségur, Jacques, Gatenby, Robert A, Rivoltini, Licia, Fais, Stefano
Publicado em 2010

E6 and E7 from Human Papillomavirus Type 16 Cooperate To Target the PDZ Protein Na/H Exchange Regulatory Factor 1

Por Accardi, Rosita, Rubino, Rosa, Scalise, Mariafrancesca, Gheit, Tarik, Shahzad, Naveed, Thomas, Miranda, Banks, Lawrence, Indiveri, Cesare, Sylla, Bakary S., Cardone, Rosa A., Reshkin, Stephan J., Tommasino, Massimo
Publicado em 2011

ß1 Integrin Binding Phosphorylates Ezrin at T567 to Activate a Lipid Raft Signalsome Driving Invadopodia Activity and Invasion

Por Antelmi, Ester, Cardone, Rosa A., Greco, Maria R., Rubino, Rosa, Di Sole, Francesca, Martino, Nicola A., Casavola, Valeria, Carcangiu, MariaLuisa, Moro, Loredana, Reshkin, Stephan J.
Publicado em 2013

HPV16 E7-Dependent Transformation Activates NHE1 through a PKA-RhoA-Iinduced Inhibition of p38alpha

Por Cardone, Rosa A., Busco, Giovanni, Greco, Maria R., Bellizzi, Antonia, Accardi, Rosita, Cafarelli, Antonella, Monterisi, Stefania, Carratù, Pierluigi, Casavola, Valeria, Paradiso, Angelo, Tommasino, Massimo, Reshkin, Stephan J.
Publicado em 2008

pH-Channeling in Cancer: How pH-Dependence of Cation Channels Shapes Cancer Pathophysiology

Por Pethő, Zoltán, Najder, Karolina, Carvalho, Tiago, McMorrow, Roisin, Todesca, Luca Matteo, Rugi, Micol, Bulk, Etmar, Chan, Alan, Löwik, Clemens W. G. M., Reshkin, Stephan J., Schwab, Albrecht
Publicado no Cancers (Basel) (2020)

Glycolysis, tumor metabolism, cancer growth and dissemination. A new pH-based etiopathogenic perspective and therapeutic approach to an old cancer question

Por Alfarouk, Khalid O., Verduzco, Daniel, Rauch, Cyril, Muddathir, Abdel Khalig, Adil, H. H Bashir, Elhassan, Gamal O., Ibrahim, Muntaser E., David Polo Orozco, Julian, Cardone, Rosa Angela, Reshkin, Stephan J., Harguindey, Salvador
Publicado no Oncoscience (2014)

Glycolysis, tumor metabolism, cancer growth and dissemination. A new pH-based etiopathogenic perspective and therapeutic approach to an old cancer question

Por Alfarouk, Khalid O., Verduzco, Daniel, Rauch, Cyril, Muddathir, Abdel Khalig, Bashir, Adil H. H., Elhassan, Gamal O., Ibrahim, Muntaser E., Orozco, Julian David Polo, Cardone, Rosa Angela, Reshkin, Stephan J., Harguindey, Salvador
Publicado no Oncoscience (2014)

Resistance to cancer chemotherapy: failure in drug response from ADME to P-gp

Por Alfarouk, Khalid O, Stock, Christian-Martin, Taylor, Sophie, Walsh, Megan, Muddathir, Abdel Khalig, Verduzco, Daniel, Bashir, Adil H H, Mohammed, Osama Y, Elhassan, Gamal O, Harguindey, Salvador, Reshkin, Stephan J, Ibrahim, Muntaser E, Rauch, Cyril
Publicado no Cancer Cell Int (2015)

The Interplay of Dysregulated pH and Electrolyte Imbalance in Cancer

Por Alfarouk, Khalid O., Ahmed, Samrein B. M., Ahmed, Ahmed, Elliott, Robert L., Ibrahim, Muntaser E., Ali, Heyam S., Wales, Christian C., Nourwali, Ibrahim, Aljarbou, Ahmed N., Bashir, Adil H. H., Alhoufie, Sari T. S., Alqahtani, Saad Saeed, Cardone, Rosa A., Fais, Stefano, Harguindey, Salvador, Reshkin, Stephan J.
Publicado no Cancers (Basel) (2020)