DOT1L Inhibition Sensitizes MLL-Rearranged AML to Chemotherapy

ανά Liu, Wei, Deng, Lisheng, Song, Yongcheng, Redell, Michele
Έκδοση 2014

Distinct signaling events promote resistance to mitoxantrone and etoposide in pediatric AML: a Children’s Oncology Group report

ανά Long, Xin, Gerbing, Robert B., Alonzo, Todd A., Redell, Michele S.
Τόπος έκδοσης Oncotarget (2017)

Stromal CYR61 Confers Resistance to Mitoxantrone via Spleen Tyrosine Kinase Activation in Human Acute Myeloid Leukaemia

ανά Long, Xin, Yu, Yang, Perlaky, Laszlo, Man, Tsz-Kwong, Redell, Michele S.
Τόπος έκδοσης Br J Haematol (2015)

Interleukin-6 levels predict event-free survival in pediatric AML and suggest a mechanism of chemotherapy resistance

ανά Stevens, Alexandra M., Miller, Jennifer M., Munoz, Jaime O., Gaikwad, Amos S., Redell, Michele S.
Τόπος έκδοσης Blood Adv (2017)

Stat3 signaling in acute myeloid leukemia: ligand-dependent and -independent activation and induction of apoptosis by a novel small-molecule Stat3 inhibitor

ανά Redell, Michele S., Ruiz, Marcos J., Alonzo, Todd A., Gerbing, Robert B., Tweardy, David J.
Έκδοση 2011

Synthesis, Activity and Metabolic Stability of Non-Ribose Containing Inhibitors of Histone Methyltransferase DOT1L

ανά Deng, Lisheng, Zhang, Li, Yao, Yuan, Wang, Cong, Redell, Michele S., Dong, Shuo, Song, Yongcheng
Έκδοση 2013

Ligand-induced STAT3 signaling increases at relapse and is associated with outcome in pediatric acute myeloid leukemia: a report from the Children’s Oncology Group

ανά Stevens, Alexandra M., Ruiz, Marcos J., Gerbing, Robert B., Alonzo, Todd A., Gamis, Alan S., Redell, Michele S.
Τόπος έκδοσης Haematologica (2015)

Adoptive immunotherapy for AML with CD123-engager T cells

ανά Bonifant, Challice, Torres, David, Joseph, Nicholos, Barth, Carolyn Arber, Velasquez, Mireya, Song, Xiao-Tong, Redell, Michele, Gottschalk, Stephen
Τόπος έκδοσης J Immunother Cancer (2015)

FACS analysis of Stat3/5 signaling reveals sensitivity to G-CSF and IL-6 as a significant prognostic factor in pediatric AML: a Children's Oncology Group report

ανά Redell, Michele S., Ruiz, Marcos J., Gerbing, Robert B., Alonzo, Todd A., Lange, Beverly J., Tweardy, David J., Meshinchi, Soheil
Έκδοση 2013

Assessing the intracellular fate of rhodium(II) complexes

ανά Minus, Matthew B., Kang, Marci K., Knudsen, Sarah E., Liu, Wei, Krueger, Michael J., Smith, Morgen L., Redell, Michele S., Ball, Zachary T.
Τόπος έκδοσης Chem Commun (Camb) (2016)

Drug Targeting of NR4A Nuclear Receptors for Treatment of Acute Myeloid Leukemia

ανά Boudreaux, Seth P., Duren, Ryan P., Call, Steven G., Nguyen, Loc, Freire, Pablo R, Narayanan, Padmini, Redell, Michele S., Conneely, Orla M.
Τόπος έκδοσης Leukemia (2018)

Pharmacological inhibition of LSD1 for the treatment of MLL-rearranged leukemia

ανά Feng, Zizhen, Yao, Yuan, Zhou, Chao, Chen, Fengju, Wu, Fangrui, Wei, Liping, Liu, Wei, Dong, Shuo, Redell, Michele, Mo, Qianxing, Song, Yongcheng
Τόπος έκδοσης J Hematol Oncol (2016)

Glucocorticoids Inhibit Oncogenic RUNX1-ETO in Acute Myeloid Leukemia with Chromosome Translocation t(8;21)

ανά Lu, Lianghao, Wen, Yefei, Yao, Yuan, Chen, Fengju, Wang, Guohui, Wu, Fangrui, Wu, Jingyu, Narayanan, Padmini, Redell, Michele, Mo, Qianxing, Song, Yongcheng
Τόπος έκδοσης Theranostics (2018)

CD123-Engager T Cells as a Novel Immunotherapeutic for Acute Myeloid Leukemia

ανά Bonifant, Challice L, Szoor, Arpad, Torres, David, Joseph, Nicholos, Velasquez, Mireya Paulina, Iwahori, Kota, Gaikwad, Amos, Nguyen, Phuong, Arber, Caroline, Song, Xiao-Tong, Redell, Michele, Gottschalk, Stephen
Τόπος έκδοσης Mol Ther (2016)

Management of Chronic Myeloid Leukemia (CML) in Children and Adolescents: Recommendations from the Children’s Oncology Group CML Working Group

ανά Athale, Uma, Hijiya, Nobuko, Patterson, Briana C., Bergsagel, John, Andolina, Jeffrey R., Bittencourt, Henrique, Schultz, Kirk R., Burke, Michael J, Redell, Michele S., Kolb, E. Anders, Johnston, Donna L.
Τόπος έκδοσης Pediatr Blood Cancer (2019)

Rhodium(II) proximity-labeling identifies a novel target site on STAT3 for inhibitors with potent anti-leukemia activity

ανά Minus, Matthew B., Liu, Wei, Vohidov, Farrukh, Kasembeli, Moses M., Long, Xin, Krueger, Michael, Stevens, Alexandra, Kolosov, Mikhail I., Tweardy, David J., Sison, Edward Allen R., Redell, Michele S., Ball, Zachary T.
Τόπος έκδοσης Angew Chem Int Ed Engl (2015)

Modulating TNFα activity allows transgenic IL15-Expressing CLL-1 CAR T cells to safely eliminate acute myeloid leukemia

ανά Ataca Atilla, Pinar, McKenna, Mary K, Tashiro, Haruko, Srinivasan, Madhuwanti, Mo, Feiyan, Watanabe, Norihiro, Simons, Brian Wesley, McLean Stevens, Alexandra, Redell, Michele S, Heslop, Helen E, Mamonkin, Maksim, Brenner, Malcolm K, Atilla, Erden
Τόπος έκδοσης J Immunother Cancer (2020)

Targeting STAT3 anti-apoptosis pathways with organic and hybrid organic–inorganic inhibitors

ανά Minus, Matthew B., Wang, Haopei, Munoz, Jaime O., Stevens, Alexandra M., Mangubat-Medina, Alicia E., Krueger, Michael J., Liu, Wei, Kasembeli, Moses M., Cooper, Julian C., Kolosov, Mikhail I., Tweardy, David J., Redell, Michele S., Ball, Zachary T.
Τόπος έκδοσης Org Biomol Chem (2020)

Atovaquone is active against AML by upregulating the integrated stress pathway and suppressing oxidative phosphorylation

ανά Stevens, Alexandra M., Xiang, Michael, Heppler, Lisa N., Tošić, Isidora, Jiang, Kevin, Munoz, Jaime O., Gaikwad, Amos S., Horton, Terzah M., Long, Xin, Narayanan, Padmini, Seashore, Elizabeth L., Terrell, Maci C., Rashid, Raushan, Krueger, Michael J., Mangubat-Medina, Alicia E., Ball, Zachary T., Sumazin, Pavel, Walker, Sarah R., Hamada, Yoshimasa, Oyadomari, Seiichi, Redell, Michele S., Frank, David A.
Τόπος έκδοσης Blood Adv (2019)