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FACS analysis of Stat3/5 signaling reveals sensitivity to G-CSF and IL-6 as a significant prognostic factor in pediatric AML: a Children's Oncology Group report

Signal transducer and activator of transcription 3 (Stat3) and Stat5 are critical signaling intermediates that promote survival in myeloid leukemias. We examined Stat3 and Stat5 activation patterns in resting and ligand-stimulated primary samples from pediatric patients with acute myeloid leukemia....

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Detalhes bibliográficos
Main Authors: Redell, Michele S., Ruiz, Marcos J., Gerbing, Robert B., Alonzo, Todd A., Lange, Beverly J., Tweardy, David J., Meshinchi, Soheil
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575754/
https://ncbi.nlm.nih.gov/pubmed/23243289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-04-421925
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