Prevalence and prognostic implications of CEBPA mutations in pediatric acute myeloid leukemia (AML): a report from the Children's Oncology Group

CEBPA mutations have been associated with improved outcome in adult acute myeloid leukemia (AML). We evaluated the prevalence and prognostic significance of CEBPA mutations in 847 children with AML treated on 3 consecutive pediatric trials. Two types of CEBPA mutations—N-terminal truncating mutation...

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Detalhes bibliográficos
Main Authors: Ho, Phoenix A., Alonzo, Todd A., Gerbing, Robert B., Pollard, Jessica, Stirewalt, Derek L., Hurwitz, Craig, Heerema, Nyla A., Hirsch, Betsy, Raimondi, Susana C., Lange, Beverly, Franklin, Janet L., Radich, Jerald P., Meshinchi, Soheil
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
Assuntos:
Clinical Trials and Observations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943755/
https://ncbi.nlm.nih.gov/pubmed/19304957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-10-184747
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