Inter-Species Differences in Regulation of the Progranulin–Sortilin Axis in TDP-43 Cell Models of Neurodegeneration

por Gumina, Valentina, Onesto, Elisa, Colombrita, Claudia, Maraschi, AnnaMaria, Silani, Vincenzo, Ratti, Antonia
Publicado no Int J Mol Sci (2019)

The 3' untranslated region of human Cyclin-Dependent Kinase 5 Regulatory subunit 1 contains regulatory elements affecting transcript stability

por Moncini, Silvia, Bevilacqua, Annamaria, Venturin, Marco, Fallini, Claudia, Ratti, Antonia, Nicolin, Angelo, Riva, Paola
Publicado em 2007

TDP-43 and FUS RNA-binding Proteins Bind Distinct Sets of Cytoplasmic Messenger RNAs and Differently Regulate Their Post-transcriptional Fate in Motoneuron-like Cells

por Colombrita, Claudia, Onesto, Elisa, Megiorni, Francesca, Pizzuti, Antonio, Baralle, Francisco E., Buratti, Emanuele, Silani, Vincenzo, Ratti, Antonia
Publicado em 2012

TDP-43 and NOVA-1 RNA-binding proteins as competitive splicing regulators of the schizophrenia-associated TNIK gene

por Gumina, Valentina, Colombrita, Claudia, Fallini, Claudia, Bossolasco, Patrizia, Maraschi, Anna Maria, Landers, John E., Silani, Vincenzo, Ratti, Antonia
Publicado no Biochim Biophys Acta Gene Regul Mech (2019)

Molecular Signatures of Amyotrophic Lateral Sclerosis Disease Progression in Hind and Forelimb Muscles of an SOD1(G93A) Mouse Model

por Capitanio, Daniele, Vasso, Michele, Ratti, Antonia, Grignaschi, Giuliano, Volta, Manuela, Moriggi, Manuela, Daleno, Cristina, Bendotti, Caterina, Silani, Vincenzo, Gelfi, Cecilia
Publicado em 2012

Reprogramming fibroblasts and peripheral blood cells from a C9ORF72 patient: A proof‐of‐principle study

por Bardelli, Donatella, Sassone, Francesca, Colombrita, Claudia, Volpe, Clara, Gumina, Valentina, Peverelli, Silvia, Catusi, Ilaria, Ratti, Antonia, Silani, Vincenzo, Bossolasco, Patrizia
Publicado no J Cell Mol Med (2020)

Modulation of actin polymerization affects nucleocytoplasmic transport in multiple forms of amyotrophic lateral sclerosis

por Giampetruzzi, Anthony, Danielson, Eric W., Gumina, Valentina, Jeon, Maryangel, Boopathy, Sivakumar, Brown, Robert H., Ratti, Antonia, Landers, John E., Fallini, Claudia
Publicado no Nat Commun (2019)

Dendritic targeting of short and long 3′ UTR BDNF mRNA is regulated by BDNF or NT-3 and distinct sets of RNA-binding proteins

por Vicario, Annalisa, Colliva, Andrea, Ratti, Antonia, Davidovic, Laetitia, Baj, Gabriele, Gricman, Łukasz, Colombrita, Claudia, Pallavicini, Alberto, Jones, Kevin R., Bardoni, Barbara, Tongiorgi, Enrico
Publicado no Front Mol Neurosci (2015)

Gene-specific mitochondria dysfunctions in human TARDBP and C9ORF72 fibroblasts

por Onesto, Elisa, Colombrita, Claudia, Gumina, Valentina, Borghi, Maria Orietta, Dusi, Sabrina, Doretti, Alberto, Fagiolari, Gigliola, Invernizzi, Federica, Moggio, Maurizio, Tiranti, Valeria, Silani, Vincenzo, Ratti, Antonia
Publicado no Acta Neuropathol Commun (2016)

Oligoclonal bands in the cerebrospinal fluid of amyotrophic lateral sclerosis patients with disease-associated mutations

por Ticozzi, Nicola, Tiloca, Cinzia, Mencacci, Niccolò E., Morelli, Claudia, Doretti, Alberto, Rusconi, Daniela, Colombrita, Claudia, Sangalli, Davide, Verde, Federico, Finelli, Palma, Messina, Stefano, Ratti, Antonia, Silani, Vincenzo
Publicado em 2012

Analysis of hnRNPA1, A2/B1, and A3 genes in patients with amyotrophic lateral sclerosis

por Calini, Daniela, Corrado, Lucia, Del Bo, Roberto, Gagliardi, Stella, Pensato, Viviana, Verde, Federico, Corti, Stefania, Mazzini, Letizia, Milani, Pamela, Castellotti, Barbara, Bertolin, Cinzia, Sorarù, Gianni, Cereda, Cristina, Comi, Giacomo P., D’Alfonso, Sandra, Gellera, Cinzia, Ticozzi, Nicola, Landers, John E., Ratti, Antonia, Silani, Vincenzo
Publicado no Neurobiol Aging (2013)

TDP-43 real-time quaking induced conversion reaction optimization and detection of seeding activity in CSF of amyotrophic lateral sclerosis and frontotemporal dementia patients

por Scialò, Carlo, Tran, Thanh Hoa, Salzano, Giulia, Novi, Giovanni, Caponnetto, Claudia, Chiò, Adriano, Calvo, Andrea, Canosa, Antonio, Moda, Fabio, Caroppo, Paola, Silani, Vincenzo, Ticozzi, Nicola, Ratti, Antonia, Borroni, Barbara, Benussi, Luisa, Ghidoni, Roberta, Furlanis, Giovanni, Manganotti, Paolo, Senigagliesi, Beatrice, Parisse, Pietro, Brasselet, Romain, Buratti, Emanuele, Legname, Giuseppe
Publicado no Brain Commun (2020)

Paraoxonase Gene Mutations in Amyotrophic Lateral Sclerosis

por Ticozzi, Nicola, LeClerc, Ashley Lyn, Keagle, Pamela, Glass, Jonathan D., Wills, Anne-Marie, van Blitterswijk, Marka, Bosco, Daryl A., Rodriguez-Leyva, Ildefonso, Gellera, Cinzia, Ratti, Antonia, Taroni, Franco, McKenna-Yasek, Diane M., Sapp, Peter C., Silani, Vincenzo, Furlong, Clement E., Brown, Robert H., Landers, John E.
Publicado em 2010

Phosphorylated neurofilament heavy chain: a biomarker of survival for C9ORF72-associated amyotrophic lateral sclerosis

por Gendron, Tania F., Daughrity, Lillian M., Heckman, Michael G., Diehl, Nancy N., Wuu, Joanne, Miller, Timothy M., Pastor, Pau, Trojanowski, John Q., Grossman, Murray, Berry, James D., Hu, William T., Ratti, Antonia, Benatar, Michael, Silani, Vincenzo, Glass, Jonathan D., Floeter, Mary Kay, Jeromin, Andreas, Boylan, Kevin B., Petrucelli, Leonard
Publicado no Ann Neurol (2017)

Screening of the PFN1 gene in sporadic ALS and in FTD

por Tiloca, Cinzia, Ticozzi, Nicola, Pensato, Viviana, Corrado, Lucia, Del Bo, Roberto, Bertolin, Cinzia, Fenoglio, Chiara, Gagliardi, Stella, Calini, Daniela, Lauria, Giuseppe, Castellotti, Barbara, Bagarotti, Alessandra, Corti, Stefania, Galimberti, Daniela, Cagnin, Annachiara, Gabelli, Carlo, Ranieri, Michela, Ceroni, Mauro, Siciliano, Gabriele, Mazzini, Letizia, Cereda, Cristina, Scarpini, Elio, Sorarù, Gianni, Comi, Giacomo P., D'Alfonso, Sandra, Gellera, Cinzia, Ratti, Antonia, Landers, John E., Silani, Vincenzo
Publicado em 2012

TUBA4A gene analysis in sporadic amyotrophic lateral sclerosis: identification of novel mutations

por Pensato, Viviana, Tiloca, Cinzia, Corrado, Lucia, Bertolin, Cinzia, Sardone, Valentina, Del Bo, Roberto, Calini, Daniela, Mandrioli, Jessica, Lauria, Giuseppe, Mazzini, Letizia, Querin, Giorgia, Ceroni, Mauro, Cantello, Roberto, Corti, Stefania, Castellotti, Barbara, Soldà, Giulia, Duga, Stefano, Comi, Giacomo P., Cereda, Cristina, Sorarù, Gianni, D’Alfonso, Sandra, Taroni, Franco, Shaw, Christopher E., Landers, John E., Ticozzi, Nicola, Ratti, Antonia, Gellera, Cinzia, Silani, Vincenzo
Publicado no J Neurol (2015)

Discovery of a Biomarker and Lead Small Molecules to Target r(GGGGCC)-Associated Defects in c9FTD/ALS

por Su, Zhaoming, Zhang, Yongjie, Gendron, Tania F., Bauer, Peter O., Chew, Jeannie, Yang, Wang-Yong, Fostvedt, Erik, Jansen-West, Karen, Belzil, Veronique V., Desaro, Pamela, Johnston, Amelia, Overstreet, Karen, Oh, Seok-Yoon, Todd, Peter K., Berry, James D., Cudkowicz, Merit E., Boeve, Bradley F., Dickson, Dennis, Floeter, Mary Kay, Traynor, Bryan J., Morelli, Claudia, Ratti, Antonia, Silani, Vincenzo, Rademakers, Rosa, Brown, Robert H., Rothstein, Jeffrey D., Boylan, Kevin B., Petrucelli, Leonard, Disney, Matthew D.
Publicado no Neuron (2014)

The role of de novo mutations in the development of amyotrophic lateral sclerosis

por van Doormaal, Perry T.C., Ticozzi, Nicola, Weishaupt, Jochen H., Kenna, Kevin, Diekstra, Frank P., Verde, Federico, Andersen, Peter M., Dekker, Annelot M., Tiloca, Cinzia, Marroquin, Nicolai, Overste, Daniel J., Pensato, Viviana, Nürnberg, Peter, Pulit, Sara L., Schellevis, Raymond D., Calini, Daniela, Altmüller, Janine, Francioli, Laurent C., Muller, Bernard, Castellotti, Barbara, Motameny, Susanne, Ratti, Antonia, Wolf, Joachim, Gellera, Cinzia, Ludolph, Albert C., van den Berg, Leonard H., Kubisch, Christian, Landers, John E., Veldink, Jan H., Silani, Vincenzo, Volk, Alexander E.
Publicado no Hum Mutat (2017)

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

por Pourhaghighi, Reza, Ash, Peter E. A., Phanse, Sadhna, Goebels, Florian, Hu, Lucas Z. M., Chen, Siwei, Zhang, Yingying, Wierbowski, Shayne D., Boudeau, Samantha, Moutaoufik, Mohamed T., Malty, Ramy H., Malolepsza, Edyta, Tsafou, Kalliopi, Nathan, Aparna, Cromar, Graham, Guo, Hongbo, Al Abdullatif, Ali, Apicco, Daniel J., Becker, Lindsay A., Gitler, Aaron D., Pulst, Stefan M., Youssef, Ahmed, Hekman, Ryan, Havugimana, Pierre C., White, Carl A., Blum, Benjamin C., Ratti, Antonia, Bryant, Camron D., Parkinson, John, Lage, Kasper, Babu, Mohan, Yu, Haiyuan, Bader, Gary D., Wolozin, Benjamin, Emili, Andrew
Publicado no Cell Syst (2020)

ALS-associated missense and nonsense TBK1 mutations can both cause loss of kinase function

por de Majo, Martina, Topp, Simon D., Smith, Bradley N., Nishimura, Agnes L., Chen, Han-Jou, Gkazi, Athina Soragia, Miller, Jack, Wong, Chun Hao, Vance, Caroline, Baas, Frank, ten Asbroek, Anneloor L.M.A., Kenna, Kevin P., Ticozzi, Nicola, Redondo, Alberto Garcia, Esteban-Pérez, Jesús, Tiloca, Cinzia, Verde, Federico, Duga, Stefano, Morrison, Karen E., Shaw, Pamela J., Kirby, Janine, Turner, Martin R., Talbot, Kevin, Hardiman, Orla, Glass, Jonathan D., de Belleroche, Jacqueline, Gellera, Cinzia, Ratti, Antonia, Al-Chalabi, Ammar, Brown, Robert H., Silani, Vincenzo, Landers, John E., Shaw, Christopher E.
Publicado no Neurobiol Aging (2018)