Paraoxonase Gene Mutations in Amyotrophic Lateral Sclerosis

Three clustered, homologous paraoxonase genes (PON1, PON2 and PON3) have roles in preventing lipid oxidation and detoxifying organophosphates. Recent reports describe a genetic association between the PON genes and sporadic amyotrophic lateral sclerosis (ALS). We now report that in genomic DNA from...

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Autores principales: Ticozzi, Nicola, LeClerc, Ashley Lyn, Keagle, Pamela, Glass, Jonathan D., Wills, Anne-Marie, van Blitterswijk, Marka, Bosco, Daryl A., Rodriguez-Leyva, Ildefonso, Gellera, Cinzia, Ratti, Antonia, Taroni, Franco, McKenna-Yasek, Diane M., Sapp, Peter C., Silani, Vincenzo, Furlong, Clement E., Brown, Robert H., Landers, John E.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945725/
https://ncbi.nlm.nih.gov/pubmed/20582942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.21993
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