Nonactin Biosynthesis: the Product of nonS Catalyzes the Formation of the Furan Ring of Nonactic Acid

Por Woo, Anton J., Strohl, William R., Priestley, Nigel D.
Publicado em 1999

Nonactin biosynthesis: setting limits on what can be achieved with precursor-directed biosynthesis

Por Kusche, Brian R., Phillips, Joshua B., Priestley, Nigel D.
Publicado em 2008

Purification, Properties, and Characterization of Recombinant Streptomyces sp. Strain C5 DoxA, a Cytochrome P-450 Catalyzing Multiple Steps in Doxorubicin Biosynthesis

Por Walczak, Robbie J., Dickens, Michael L., Priestley, Nigel D., Strohl, William R.
Publicado em 1999

The alternating pattern of stereochemistry in the nonactin macrocycle is required for antibacterial activity and efficient ion binding

Por Kusche, Brian R., Smith, Adrienne E., McGuirl, Michele A., Priestley, Nigel D.
Publicado em 2009

The crystal structure of Candida glabrata dihydrofolate reductase drives new inhibitor design toward efficacious antifungal agents

Por Liu, Jieying, Bolstad, David B., Smith, Adrienne E., Priestley, Nigel D., Wright, Dennis L., Anderson, Amy C.
Publicado em 2008

Probing the active site of Candida glabrata dihydrofolate reductase with high resolution crystal structures and the synthesis of new inhibitors

Por Liu, Jieying, Bolstad, David B., Smith, Adrienne E., Priestley, Nigel D., Wright, Dennis L., Anderson, Amy C.
Publicado em 2009

Crystal Structures of Klebsiella pneumoniae Dihydrofolate Reductase Bound to Propargyl-Linked Antifolates Reveal Features for Potency and Selectivity

Por Lamb, Kristen M., Lombardo, Michael N., Alverson, Jeremy, Priestley, Nigel D., Wright, Dennis L., Anderson, Amy C.
Publicado no Antimicrob Agents Chemother (2014)

In Vitro Biological Activity and Structural Analysis of 2,4-Diamino-5-(2’-arylpropargyl)pyrimidine Inhibitors of Candida albicans

Por Paulsen, Janet L., Liu, Jieying, Bolstad, David B., Smith, Adrienne, Priestley, Nigel D., Wright, Dennis L., Anderson, Amy C.
Publicado em 2009

The Berkeleylactones, Antibiotic Macrolides from Fungal Coculture

Por Stierle, Andrea A., Stierle, Donald B., Decato, Daniel, Priestley, Nigel D., Alverson, Jeremy B., Hoody, John, McGrath, Kelly, Klepacki, Dorota
Publicado no J Nat Prod (2017)

Pharmaceutical Analysis of a Novel Propargyl-linked Antifolate Antibiotic in the Mouse

Por Hoody, John, Alverson, Jeremy B., Keshipeddy, Santosh, Barney, Patrick A., Walker, Larissa, Anderson, Amy C., Wright, Dennis L., Priestley, Nigel D.
Publicado no J Chromatogr B Analyt Technol Biomed Life Sci (2017)

Synthetic and Crystallographic Studies of a New Inhibitor Series Targeting Bacillus anthracis Dihydrofolate Reductase

Por Beierlein, Jennifer M., Frey, Kathleen M., Bolstad, David B., Pelphrey, Phillip M., Joska, Tammy M., Smith, Adrienne E., Priestley, Nigel D., Wright, Dennis L., Anderson, Amy C.
Publicado em 2008

Toward New Therapeutics for Skin and Soft Tissue Infections: Propargyl-Linked Antifolates Are Potent Inhibitors of MRSA and Streptococcus pyogenes

Por Viswanathan, Kishore, Frey, Kathleen M., Scocchera, Eric W., Martin, Brooke D., Swain III, P. Whitney, Alverson, Jeremy B., Priestley, Nigel D., Anderson, Amy C., Wright, Dennis L.
Publicado em 2012

Charged Nonclassical Antifolates with Activity Against Gram-Positive and Gram-Negative Pathogens

Por Scocchera, Eric, Reeve, Stephanie M., Keshipeddy, Santosh, Lombardo, Michael N., Hajian, Behnoush, Sochia, Adrienne E., Alverson, Jeremy B., Priestley, Nigel D., Anderson, Amy C., Wright, Dennis L.
Publicado no ACS Med Chem Lett (2016)

Natural Product Derivatives with Bactericidal Activity Against Gram-positive Pathogens Including Methicillin-resistant Staphylococcus aureus and Vancomycin-resistant Enterococcus f...

Por Phillips, Joshua B., Smith, Adrienne E., Kusche, Brian R., Bessette, Bradley A., Swain, P. Whitney, Bergmeier, Stephen C., McMills, Mark C., Wright, Dennis L., Priestley, Nigel D.
Publicado no Bioorg Med Chem Lett (2010)

Propargyl-Linked Antifolates are Dual Inhibitors of Candida albicans and Candida glabrata

Por G-Dayanandan, Narendran, Paulsen, Janet L., Viswanathan, Kishore, Keshipeddy, Santosh, Lombardo, Michael N., Zhou, Wangda, Lamb, Kristen M., Sochia, Adrienne E., Alverson, Jeremy B., Priestley, Nigel D., Wright, Dennis L., Anderson, Amy C.
Publicado em 2014