The parasitic worm product ES-62 up-regulates IL-22 production by γδ T cells in the murine model of Collagen-Induced Arthritis

von Harnett, Margaret M., Harnett, William, Pineda, Miguel A.
Veröffentlicht in Inflamm Cell Signal (2014)

ES‐62 Protects Against Collagen‐Induced Arthritis by Resetting Interleukin‐22 Toward Resolution of Inflammation in the Joints

von Pineda, Miguel A., Rodgers, David T., Al‐Riyami, Lamyaa, Harnett, William, Harnett, Margaret M.
Veröffentlicht in Arthritis Rheumatol (2014)

Development of Acanthocheilonema viteae in Meriones shawi: Absence of microfilariae and production of active ES‐62

von Lumb, Felicity E., Doonan, James, Corbet, Marlene, Pineda, Miguel A., M. Harnett, Margaret, Harnett, William
Veröffentlicht in Parasite Immunol (2020)

Protection against collagen-induced arthritis in mice afforded by the parasitic worm product, ES-62, is associated with restoration of the levels of interleukin-10-producing B cell...

von Rodgers, David T, Pineda, Miguel A, McGrath, Mairi A, Al-Riyami, Lamyaa, Harnett, William, Harnett, Margaret M
Veröffentlicht 2014

Protective effect of small molecule analogues of the Acanthocheilonema viteae secreted product ES-62 on oxazolone-induced ear inflammation

von Al-Riyami, Lamyaa, Rodgers, David T., Rzepecka, Justyna, Pineda, Miguel A., Suckling, Colin J., Harnett, Margaret M., Harnett, William
Veröffentlicht in Exp Parasitol (2015)

From Christian de Duve to Yoshinori Ohsumi: More to autophagy than just dining at home

von Harnett, Margaret M., Pineda, Miguel A., Latré de Laté, Perle, Eason, Russell J., Besteiro, Sébastien, Harnett, William, Langsley, Gordon
Veröffentlicht in Biomed J (2017)

Dendritic cells provide a therapeutic target for synthetic small molecule analogues of the parasitic worm product, ES-62

von Lumb, Felicity E., Doonan, James, Bell, Kara S., Pineda, Miguel A., Corbet, Marlene, Suckling, Colin J., Harnett, Margaret M., Harnett, William
Veröffentlicht in Sci Rep (2017)

The Parasitic Worm Product ES-62 Targets Myeloid Differentiation Factor 88–Dependent Effector Mechanisms to Suppress Antinuclear Antibody Production and Proteinuria in MRL/lpr Mice...

von Rodgers, David T, McGrath, Mairi A, Pineda, Miguel A, Al-Riyami, Lamyaa, Rzepecka, Justyna, Lumb, Felicity, Harnett, William, Harnett, Margaret M
Veröffentlicht in Arthritis Rheumatol (2015)

Protection Against Arthritis by the Parasitic Worm Product ES-62, and Its Drug-Like Small Molecule Analogues, Is Associated With Inhibition of Osteoclastogenesis

von Doonan, James, Lumb, Felicity E., Pineda, Miguel A., Tarafdar, Anuradha, Crowe, Jenny, Khan, Aneesah M., Suckling, Colin J., Harnett, Margaret M., Harnett, William
Veröffentlicht in Front Immunol (2018)

The parasitic worm product ES-62 normalises the gut microbiota bone marrow axis in inflammatory arthritis

von Doonan, James, Tarafdar, Anuradha, Pineda, Miguel A., Lumb, Felicity E., Crowe, Jenny, Khan, Aneesah M., Hoskisson, Paul A., Harnett, Margaret M., Harnett, William
Veröffentlicht in Nat Commun (2019)

The helminth product, ES-62 modulates dendritic cell responses by inducing the selective autophagolysosomal degradation of TLR-transducers, as exemplified by PKCδ

von Eason, Russell J., Bell, Kara S., Marshall, Fraser A., Rodgers, David T., Pineda, Miguel A., Steiger, Christina N., Al-Riyami, Lamyaa, Harnett, William, Harnett, Margaret M.
Veröffentlicht in Sci Rep (2016)

The parasitic worm product ES-62 protects against collagen-induced arthritis by resetting the gut-bone marrow axis in a microbiome-dependent manner

von Harnett, Margaret M., Doonan, James, Tarafdar, Anuradha, Pineda, Miguel A., Duncombe-Moore, Josephine, Buitrago, Geraldine, Pan, Piaopiao, Hoskisson, Paul A., Selman, Colin, Harnett, William
Veröffentlicht in Front Trop Dis (2024)

Designing Anti-inflammatory Drugs from Parasitic Worms: A Synthetic Small Molecule Analogue of the Acanthocheilonema viteae Product ES-62 Prevents Development of Collagen-Induced A...

von Al-Riyami, Lamyaa, Pineda, Miguel A., Rzepecka, Justyna, Huggan, Judith K., Khalaf, Abedawn I., Suckling, Colin J., Scott, Fraser J., Rodgers, David T., Harnett, Margaret M., Harnett, William
Veröffentlicht 2013

The parasitic worm product ES-62 promotes health- and life-span in a high calorie diet-accelerated mouse model of ageing

von Crowe, Jenny, Lumb, Felicity E., Doonan, James, Broussard, Margaux, Tarafdar, Anuradha, Pineda, Miguel A., Landabaso, Carmen, Mulvey, Lorna, Hoskisson, Paul A., Babayan, Simon A., Selman, Colin, Harnett, William, Harnett, Margaret M.
Veröffentlicht in PLoS Pathog (2020)

Prophylactic and therapeutic treatment with a synthetic analogue of a parasitic worm product prevents experimental arthritis and inhibits IL-1β production via NRF2-mediated counter...

von Rzepecka, Justyna, Pineda, Miguel A., Al-Riyami, Lamyaa, Rodgers, David T., Huggan, Judith K., Lumb, Felicity E., Khalaf, Abedawn I., Meakin, Paul J., Corbet, Marlene, Ashford, Michael L., Suckling, Colin J., Harnett, Margaret M., Harnett, William
Veröffentlicht in J Autoimmun (2015)

Loss of α2-6 sialylation promotes the transformation of synovial fibroblasts into a pro-inflammatory phenotype in arthritis

von Wang, Yilin, Khan, Aneesah, Antonopoulos, Aristotelis, Bouché, Laura, Buckley, Christopher D., Filer, Andrew, Raza, Karim, Li, Kun-Ping, Tolusso, Barbara, Gremese, Elisa, Kurowska-Stolarska, Mariola, Alivernini, Stefano, Dell, Anne, Haslam, Stuart M., Pineda, Miguel A.
Veröffentlicht in Nat Commun (2021)