The Parasitic Worm Product ES-62 Targets Myeloid Differentiation Factor 88–Dependent Effector Mechanisms to Suppress Antinuclear Antibody Production and Proteinuria in MRL/lpr Mice

OBJECTIVE: The hygiene hypothesis suggests that parasitic helminths (worms) protect against the development of autoimmune disease via a serendipitous side effect of worm-derived immunomodulators that concomitantly promote parasite survival and limit host pathology. The aim of this study was to inves...

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Detalhes bibliográficos
Publicado no:Arthritis Rheumatol
Main Authors: Rodgers, David T, McGrath, Mairi A, Pineda, Miguel A, Al-Riyami, Lamyaa, Rzepecka, Justyna, Lumb, Felicity, Harnett, William, Harnett, Margaret M
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Systemic Lupus Erythematosus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409857/
https://ncbi.nlm.nih.gov/pubmed/25546822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39004
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