The parasitic worm product ES-62 up-regulates IL-22 production by γδ T cells in the murine model of Collagen-Induced Arthritis

Por Harnett, Margaret M., Harnett, William, Pineda, Miguel A.
Publicado no Inflamm Cell Signal (2014)

ES‐62 Protects Against Collagen‐Induced Arthritis by Resetting Interleukin‐22 Toward Resolution of Inflammation in the Joints

Por Pineda, Miguel A., Rodgers, David T., Al‐Riyami, Lamyaa, Harnett, William, Harnett, Margaret M.
Publicado no Arthritis Rheumatol (2014)

Protection against collagen-induced arthritis in mice afforded by the parasitic worm product, ES-62, is associated with restoration of the levels of interleukin-10-producing B cell...

Por Rodgers, David T, Pineda, Miguel A, McGrath, Mairi A, Al-Riyami, Lamyaa, Harnett, William, Harnett, Margaret M
Publicado em 2014

Protective effect of small molecule analogues of the Acanthocheilonema viteae secreted product ES-62 on oxazolone-induced ear inflammation

Por Al-Riyami, Lamyaa, Rodgers, David T., Rzepecka, Justyna, Pineda, Miguel A., Suckling, Colin J., Harnett, Margaret M., Harnett, William
Publicado no Exp Parasitol (2015)

Dendritic cells provide a therapeutic target for synthetic small molecule analogues of the parasitic worm product, ES-62

Por Lumb, Felicity E., Doonan, James, Bell, Kara S., Pineda, Miguel A., Corbet, Marlene, Suckling, Colin J., Harnett, Margaret M., Harnett, William
Publicado no Sci Rep (2017)

The Parasitic Worm Product ES-62 Targets Myeloid Differentiation Factor 88–Dependent Effector Mechanisms to Suppress Antinuclear Antibody Production and Proteinuria in MRL/lpr Mice...

Por Rodgers, David T, McGrath, Mairi A, Pineda, Miguel A, Al-Riyami, Lamyaa, Rzepecka, Justyna, Lumb, Felicity, Harnett, William, Harnett, Margaret M
Publicado no Arthritis Rheumatol (2015)

The helminth product, ES-62 modulates dendritic cell responses by inducing the selective autophagolysosomal degradation of TLR-transducers, as exemplified by PKCδ

Por Eason, Russell J., Bell, Kara S., Marshall, Fraser A., Rodgers, David T., Pineda, Miguel A., Steiger, Christina N., Al-Riyami, Lamyaa, Harnett, William, Harnett, Margaret M.
Publicado no Sci Rep (2016)

Designing Anti-inflammatory Drugs from Parasitic Worms: A Synthetic Small Molecule Analogue of the Acanthocheilonema viteae Product ES-62 Prevents Development of Collagen-Induced A...

Por Al-Riyami, Lamyaa, Pineda, Miguel A., Rzepecka, Justyna, Huggan, Judith K., Khalaf, Abedawn I., Suckling, Colin J., Scott, Fraser J., Rodgers, David T., Harnett, Margaret M., Harnett, William
Publicado em 2013

Prophylactic and therapeutic treatment with a synthetic analogue of a parasitic worm product prevents experimental arthritis and inhibits IL-1β production via NRF2-mediated counter...

Por Rzepecka, Justyna, Pineda, Miguel A., Al-Riyami, Lamyaa, Rodgers, David T., Huggan, Judith K., Lumb, Felicity E., Khalaf, Abedawn I., Meakin, Paul J., Corbet, Marlene, Ashford, Michael L., Suckling, Colin J., Harnett, Margaret M., Harnett, William
Publicado no J Autoimmun (2015)