ES‐62 Protects Against Collagen‐Induced Arthritis by Resetting Interleukin‐22 Toward Resolution of Inflammation in the Joints

Por Pineda, Miguel A., Rodgers, David T., Al‐Riyami, Lamyaa, Harnett, William, Harnett, Margaret M.
Publicado no Arthritis Rheumatol (2014)

Protection against collagen-induced arthritis in mice afforded by the parasitic worm product, ES-62, is associated with restoration of the levels of interleukin-10-producing B cell...

Por Rodgers, David T, Pineda, Miguel A, McGrath, Mairi A, Al-Riyami, Lamyaa, Harnett, William, Harnett, Margaret M
Publicado em 2014

The Carbohydrate-linked Phosphorylcholine of the Parasitic Nematode Product ES-62 Modulates Complement Activation

Por Ahmed, Umul Kulthum, Maller, N. Claire, Iqbal, Asif J., Al-Riyami, Lamyaa, Harnett, William, Raynes, John G.
Publicado no J Biol Chem (2016)

Protective effect of small molecule analogues of the Acanthocheilonema viteae secreted product ES-62 on oxazolone-induced ear inflammation

Por Al-Riyami, Lamyaa, Rodgers, David T., Rzepecka, Justyna, Pineda, Miguel A., Suckling, Colin J., Harnett, Margaret M., Harnett, William
Publicado no Exp Parasitol (2015)

Mast Cell Subsets and Their Functional Modulation by the Acanthocheilonema viteae Product ES-62

Por Ball, Dimity H., Tay, Hwee Kee, Bell, Kara S., Coates, Michelle L., Al-Riyami, Lamyaa, Rzepecka, Justyna, Harnett, William, Harnett, Margaret M.
Publicado em 2013

The Parasitic Worm Product ES-62 Targets Myeloid Differentiation Factor 88–Dependent Effector Mechanisms to Suppress Antinuclear Antibody Production and Proteinuria in MRL/lpr Mice...

Por Rodgers, David T, McGrath, Mairi A, Pineda, Miguel A, Al-Riyami, Lamyaa, Rzepecka, Justyna, Lumb, Felicity, Harnett, William, Harnett, Margaret M
Publicado no Arthritis Rheumatol (2015)

The helminth product, ES-62, protects against airway inflammation by resetting the Th cell phenotype

Por Rzepecka, Justyna, Siebeke, Ivonne, Coltherd, Jennifer C., Kean, Dorothy E., Steiger, Christina N., Al-Riyami, Lamyaa, McSharry, Charles, Harnett, Margaret M., Harnett, William
Publicado em 2013

The helminth product, ES-62 modulates dendritic cell responses by inducing the selective autophagolysosomal degradation of TLR-transducers, as exemplified by PKCδ

Por Eason, Russell J., Bell, Kara S., Marshall, Fraser A., Rodgers, David T., Pineda, Miguel A., Steiger, Christina N., Al-Riyami, Lamyaa, Harnett, William, Harnett, Margaret M.
Publicado no Sci Rep (2016)

The immunomodulatory parasitic worm product ES-62 reduces lupus-associated accelerated atherosclerosis in a mouse model

Por Aprahamian, Tamar R., Zhong, Xuemei, Amir, Shahzada, Binder, Christoph J., Chiang, Lo-Ku, Al-Riyami, Lamyaa, Gharakhanian, Raffi, Harnett, Margaret M., Harnett, William, Rifkin, Ian R.
Publicado no Int J Parasitol (2015)

The role of individual protein kinase C isoforms in mouse mast cell function and their targeting by the immunomodulatory parasitic worm product, ES-62

Por Bell, Kara S., Al-Riyami, Lamyaa, Lumb, Felicity E., Britton, Graham J., Poole, Alastair W., Williams, Christopher M., Braun, Ursula, Leitges, Michael, Harnett, Margaret M., Harnett, William
Publicado no Immunol Lett (2015)

Designing Anti-inflammatory Drugs from Parasitic Worms: A Synthetic Small Molecule Analogue of the Acanthocheilonema viteae Product ES-62 Prevents Development of Collagen-Induced A...

Por Al-Riyami, Lamyaa, Pineda, Miguel A., Rzepecka, Justyna, Huggan, Judith K., Khalaf, Abedawn I., Suckling, Colin J., Scott, Fraser J., Rodgers, David T., Harnett, Margaret M., Harnett, William
Publicado em 2013

Small molecule analogues of the immunomodulatory parasitic helminth product ES-62 have anti-allergy properties

Por Rzepecka, Justyna, Coates, Michelle L., Saggar, Moninder, Al-Riyami, Lamyaa, Coltherd, Jennifer, Tay, Hwee Kee, Huggan, Judith K., Janicova, Lucia, Khalaf, Abedawn I., Siebeke, Ivonne, Suckling, Colin J., Harnett, Margaret M., Harnett, William
Publicado em 2014

Prophylactic and therapeutic treatment with a synthetic analogue of a parasitic worm product prevents experimental arthritis and inhibits IL-1β production via NRF2-mediated counter...

Por Rzepecka, Justyna, Pineda, Miguel A., Al-Riyami, Lamyaa, Rodgers, David T., Huggan, Judith K., Lumb, Felicity E., Khalaf, Abedawn I., Meakin, Paul J., Corbet, Marlene, Ashford, Michael L., Suckling, Colin J., Harnett, Margaret M., Harnett, William
Publicado no J Autoimmun (2015)