ES‐62 Protects Against Collagen‐Induced Arthritis by Resetting Interleukin‐22 Toward Resolution of Inflammation in the Joints

OBJECTIVE: The parasitic worm–derived immunomodulator ES‐62 protects against disease in the mouse collagen‐induced arthritis (CIA) model of rheumatoid arthritis (RA) by suppressing pathogenic interleukin‐17 (IL‐17) responses. The Th17‐associated cytokine IL‐22 also appears to have a pathogenic role...

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Detalhes bibliográficos
Publicado no:Arthritis Rheumatol
Main Authors: Pineda, Miguel A., Rodgers, David T., Al‐Riyami, Lamyaa, Harnett, William, Harnett, Margaret M.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2014
Assuntos:
Experimental Arthritis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737104/
https://ncbi.nlm.nih.gov/pubmed/24497523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38392
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