Small molecule analogues of the immunomodulatory parasitic helminth product ES-62 have anti-allergy properties

ES-62, a glycoprotein secreted by the filarial nematode Acanthocheilonema viteae, exhibits anti-inflammatory properties by virtue of covalently attached phosphorylcholine moieties. Screening of a library of ES-62 phosphorylcholine-based small molecule analogues (SMAs) revealed that two compounds, te...

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Detalhes bibliográficos
Main Authors: Rzepecka, Justyna, Coates, Michelle L., Saggar, Moninder, Al-Riyami, Lamyaa, Coltherd, Jennifer, Tay, Hwee Kee, Huggan, Judith K., Janicova, Lucia, Khalaf, Abedawn I., Siebeke, Ivonne, Suckling, Colin J., Harnett, Margaret M., Harnett, William
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science 2014
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Succinctus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119935/
https://ncbi.nlm.nih.gov/pubmed/24929132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpara.2014.05.001
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