Allosteric Modulators of GABA(B) Receptors: Mechanism of Action and Therapeutic Perspective

Por Pin, Jean-Philippe, Prézeau, Laurent
Publicado em 2007

Interaction of Protease-Activated Receptor 2 with G Proteins and β-Arrestin 1 Studied by Bioluminescence Resonance Energy Transfer

Por Ayoub, Mohammed Akli, Pin, Jean-Philippe
Publicado em 2013

Receptor-G Protein Interaction Studied by Bioluminescence Resonance Energy Transfer: Lessons from Protease-Activated Receptor 1

Por Ayoub, Mohammed Akli, Al-Senaidy, Abdulrahman, Pin, Jean-Philippe
Publicado em 2012

Analysis of positive and negative allosteric modulation in metabotropic glutamate receptors 4 and 5 with a dual ligand

Por Dalton, James A. R., Pin, Jean-Philippe, Giraldo, Jesús
Publicado no Sci Rep (2017)

Assembly-dependent Surface Targeting of the Heterodimeric GABA(B) Receptor Is Controlled by COPI but Not 14-3-3

Por Brock, Carsten, Boudier, Laure, Maurel, Damien, Blahos, Jaroslav, Pin, Jean-Philippe
Publicado em 2005

Complex GABA(B) receptor complexes: how to generate multiple functionally distinct units from a single receptor

Por Xu, Chanjuan, Zhang, Wenhua, Rondard, Philippe, Pin, Jean-Philippe, Liu, Jianfeng
Publicado em 2014

Asymmetric conformational changes in a GPCR dimer controlled by G-proteins

Por Damian, Marjorie, Martin, Aimée, Mesnier, Danielle, Pin, Jean-Philippe, Banères, Jean-Louis
Publicado em 2006

G Protein Activation by the Leukotriene B(4) Receptor Dimer: EVIDENCE FOR AN ABSENCE OF TRANS-ACTIVATION

Por Damian, Marjorie, Mary, Sophie, Martin, Aimée, Pin, Jean-Philippe, Banères, Jean-Louis
Publicado em 2008

The heptahelical domain of GABA(B2) is activated directly by CGP7930, a positive allosteric modulator of the GABA(B) receptor

Por Binet, Virginie, Brajon, Carole, Le Corre, Laurent, Acher, Francine, Pin, Jean-Philippe, Prézeau, Laurent
Publicado em 2004

The Metabotropic Glutamate Receptor mGlu7 Activates Phospholipase C, Translocates Munc-13-1 Protein, and Potentiates Glutamate Release at Cerebrocortical Nerve Terminals

Por Martín, Ricardo, Durroux, Thierry, Ciruela, Francisco, Torres, Magdalena, Pin, Jean-Philippe, Sánchez-Prieto, José
Publicado em 2010

Original Fluorescent Ligand-Based Assays Open New Perspectives in G-Protein Coupled Receptor Drug Screening

Por Cottet, Martin, Faklaris, Orestis, Zwier, Jurriaan M., Trinquet, Eric, Pin, Jean-Philippe, Durroux, Thierry
Publicado em 2011

A single subunit (GB2) is required for G-protein activation by the heterodimeric GABA(b) receptor

Por Duthey, Béatrice, Caudron, Sara, Perroy, Julie, Bettler, Bernhard, Fagni, Laurent, Pin, Jean-Philippe, Prézeau, Laurent
Publicado em 2002

Interdomain movements in metabotropic glutamate receptor activation

Por Huang, Siluo, Cao, Jianhua, Jiang, Ming, Labesse, Gilles, Liu, Jianfeng, Pin, Jean-Philippe, Rondard, Philippe
Publicado em 2011

Illuminating the activation mechanisms and allosteric properties of metabotropic glutamate receptors

Por Doumazane, Etienne, Scholler, Pauline, Fabre, Ludovic, Zwier, Jurriaan M., Trinquet, Eric, Pin, Jean-Philippe, Rondard, Philippe
Publicado em 2013

Allosteric interactions between GB1 andGB2 subunits are required for optimalGABAB receptor function

Por Galvez, Thierry, Duthey, Béatrice, Kniazeff, Julie, Blahos, Jaroslav, Rovelli, Giorgio, Bettler, Bernhard, Prézeau, Laurent, Pin, Jean-Philippe
Publicado em 2001

Common structural requirements for heptahelical domain function in class A and class C G protein-coupled receptors

Por Binet, Virginie, Duthey, Béatrice, Lecaillon, Jennifer, Vol, Claire, Quoyer, Julie, Labesse, Gilles, Pin, Jean-Philippe, Prézeau, Laurent
Publicado em 2007

Trans-activation between 7TM domains: implication in heterodimeric GABA(B) receptor activation

Por Monnier, Carine, Tu, Haijun, Bourrier, Emmanuel, Vol, Claire, Lamarque, Laurent, Trinquet, Eric, Pin, Jean-Philippe, Rondard, Philippe
Publicado em 2011

BRET and Time-resolved FRET strategy to study GPCR oligomerization: from cell lines toward native tissues

Por Cottet, Martin, Faklaris, Orestis, Maurel, Damien, Scholler, Pauline, Doumazane, Etienne, Trinquet, Eric, Pin, Jean-Philippe, Durroux, Thierry
Publicado em 2012

Closure of the Venus flytrap module of mGlu8 receptor and the activation process: Insights from mutations converting antagonists into agonists

Por Bessis, Anne-Sophie, Rondard, Philippe, Gaven, Florence, Brabet, Isabelle, Triballeau, Nicolas, Prézeau, Laurent, Acher, Francine, Pin, Jean-Philippe
Publicado em 2002

PROKR2 missense mutations associated with Kallmann syndrome impair receptor signalling activity

Por Monnier, Carine, Dodé, Catherine, Fabre, Ludovic, Teixeira, Luis, Labesse, Gilles, Pin, Jean-Philippe, Hardelin, Jean-Pierre, Rondard, Philippe
Publicado em 2009