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Allosteric Modulators of GABA(B) Receptors: Mechanism of Action and Therapeutic Perspective

γ-aminobutyric acid (GABA) plays important roles in the central nervous system, acting as a neurotransmitter on both ionotropic ligand-gated Cl(-)-channels, and metabotropic G-protein coupled receptors (GPCRs). These two types of receptors called GABA(A) (and C) and GABA(B) are the targets of major...

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Podrobná bibliografie
Hlavní autoři: Pin, Jean-Philippe, Prézeau, Laurent
Médium: Artigo
Jazyk:Inglês
Vydáno: Bentham Science Publishers Ltd. 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2656813/
https://ncbi.nlm.nih.gov/pubmed/19305802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/157015907781695919
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