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A single subunit (GB2) is required for G-protein activation by the heterodimeric GABA(b) receptor
Although G-protein coupled receptors (GPCRs) have been shown to assemble into functional homo or heteromers, the role of each protomer in G-protein activation is not known. Among the GPCRs, the γ-aminobutyric acid (GABA) type B receptor (GABA(B)R) is the only one known so far that needs two subunits...
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| Główni autorzy: | , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Biochemistry and Molecular Biology
2002
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2566549/ https://ncbi.nlm.nih.gov/pubmed/11711539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M108900200 |
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