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A single subunit (GB2) is required for G-protein activation by the heterodimeric GABA(b) receptor

Although G-protein coupled receptors (GPCRs) have been shown to assemble into functional homo or heteromers, the role of each protomer in G-protein activation is not known. Among the GPCRs, the γ-aminobutyric acid (GABA) type B receptor (GABA(B)R) is the only one known so far that needs two subunits...

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書誌詳細
主要な著者: Duthey, Béatrice, Caudron, Sara, Perroy, Julie, Bettler, Bernhard, Fagni, Laurent, Pin, Jean-Philippe, Prézeau, Laurent
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2002
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2566549/
https://ncbi.nlm.nih.gov/pubmed/11711539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M108900200
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