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Common structural requirements for heptahelical domain function in class A and class C G protein-coupled receptors

G protein-coupled receptors (GPCRs) are key players in cell communication. Several classes of such receptors have been identified. Although all GPCRs possess a heptahelical domain directly activating G proteins, important structural and sequence differences within receptors from different classes su...

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Autores principales: Binet, Virginie, Duthey, Béatrice, Lecaillon, Jennifer, Vol, Claire, Quoyer, Julie, Labesse, Gilles, Pin, Jean-Philippe, Prézeau, Laurent
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2565688/
https://ncbi.nlm.nih.gov/pubmed/17310064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M611071200
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