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Heptahelical domain of metabotropic glutamate receptor 5 behaves like rhodopsin-like receptors
Although agonists bind directly in the heptahelical domain (HD) of most class-I rhodopsin-like G protein coupled receptors (GPCRs), class-III agonists bind in the extracellular domain of their receptors. Indeed, the latter possess a large extracellular domain composed of a cysteine-rich domain and a...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC314193/ https://ncbi.nlm.nih.gov/pubmed/14691258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0304699101 |
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