Heptahelical domain of metabotropic glutamate receptor 5 behaves like rhodopsin-like receptors

Although agonists bind directly in the heptahelical domain (HD) of most class-I rhodopsin-like G protein coupled receptors (GPCRs), class-III agonists bind in the extracellular domain of their receptors. Indeed, the latter possess a large extracellular domain composed of a cysteine-rich domain and a...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Goudet, Cyril, Gaven, Florence, Kniazeff, Julie, Vol, Claire, Liu, Jiangfeng, Cohen-Gonsaud, Martin, Acher, Francine, Prézeau, Laurent, Pin, Jean Philippe
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2003
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC314193/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14691258/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0304699101
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