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Heptahelical domain of metabotropic glutamate receptor 5 behaves like rhodopsin-like receptors
Although agonists bind directly in the heptahelical domain (HD) of most class-I rhodopsin-like G protein coupled receptors (GPCRs), class-III agonists bind in the extracellular domain of their receptors. Indeed, the latter possess a large extracellular domain composed of a cysteine-rich domain and a...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2003
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC314193/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14691258/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0304699101 |
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