Oxidative Stress and Redox Modulation Potential in Type 1 Diabetes

Por Delmastro, Meghan M., Piganelli, Jon D.
Publicado em 2011

Environmental Factors Contribute to β Cell Endoplasmic Reticulum Stress and Neo-Antigen Formation in Type 1 Diabetes

Por Marré, Meghan L., Piganelli, Jon D.
Publicado no Front Endocrinol (Lausanne) (2017)

Changing the energy of an immune response

Por Delmastro-Greenwood, Meghan M, Piganelli, Jon D
Publicado em 2013

β cell ER stress and the implications for immunogenicity in type 1 diabetes

Por Marré, Meghan L., James, Eddie A., Piganelli, Jon D.
Publicado no Front Cell Dev Biol (2015)

Aberrant expression of costimulatory molecules in splenocytes of the mevalonate kinase-deficient mouse model of human hyper-IgD syndrome (HIDS)

Por Hager, Elizabeth J., Piganelli, Jon D., Tse, Hubert M., Gibson, K. Michael
Publicado em 2011

Hepatocyte Growth Factor Modulates Interleukin-6 Production in Bone Marrow Derived Macrophages: Implications for Inflammatory Mediated Diseases

Por Coudriet, Gina M., He, Jing, Trucco, Massimo, Mars, Wendy M., Piganelli, Jon D.
Publicado em 2010

T Cell Epitopes and Post-Translationally Modified Epitopes in Type 1 Diabetes

Por McGinty, John W., Marré, Meghan L., Bajzik, Veronique, Piganelli, Jon D., James, Eddie A.
Publicado no Curr Diab Rep (2015)

TRIF and IRF-3 Binding to the TNF Promoter Results in Macrophage TNF Dysregulation and Steatosis Induced by Chronic Ethanol()

Por Zhao, Xue-Jun, Dong, Qing, Bindas, Julie, Piganelli, Jon D., Magill, Amy, Reiser, Jakob, Kolls, Jay K.
Publicado em 2008

NADPH Oxidase Deficiency Regulates Th Lineage Commitment and Modulates Autoimmunity

Por Tse, Hubert M., Thayer, Terri C., Steele, Chad, Cuda, Carla M., Morel, Laurence, Piganelli, Jon D., Mathews, Clayton E.
Publicado em 2010

Modulation of Redox Balance Leaves Murine Diabetogenic TH1 T Cells “LAG-3-ing” Behind

Por Delmastro, Meghan M., Styche, Alexis J., Trucco, Massimo M., Workman, Creg J., Vignali, Dario A.A., Piganelli, Jon D.
Publicado em 2012

Leukocyte-derived extracellular superoxide dismutase does not contribute to airspace EC-SOD after interstitial pulmonary injury

Por Manni, Michelle L., Epperly, Michael W., Han, Wei, Blackwell, Timothy S., Duncan, Steven R., Piganelli, Jon D., Oury, Tim D.
Publicado em 2012

Reactive oxygen species are required for driving efficient and sustained aerobic glycolysis during CD4(+) T cell activation

Por Previte, Dana M., O’Connor, Erin C., Novak, Elizabeth A., Martins, Christina P., Mollen, Kevin P., Piganelli, Jon D.
Publicado no PLoS One (2017)

Inherent ER stress in Pancreatic Islet β cells Causes Self-Recognition by Autoreactive T Cells in Type 1 Diabetes

Por Marré, Meghan L., Profozich, Jennifer L., Coneybeer, Jorge T., Geng, Xuehui, Bertera, Suzanne, Ford, Michael J., Trucco, Massimo, Piganelli, Jon D.
Publicado no J Autoimmun (2016)

Loss of NOX-Derived Superoxide Exacerbates Diabetogenic CD4 T-Cell Effector Responses in Type 1 Diabetes

Por Padgett, Lindsey E., Anderson, Brian, Liu, Chao, Ganini, Douglas, Mason, Ronald P., Piganelli, Jon D., Mathews, Clayton E., Tse, Hubert M.
Publicado no Diabetes (2015)

Neuroprotective Efficacy from a Lipophilic Redox-Modulating Mn(III) N-Hexylpyridylporphyrin, MnTnHex-2-PyP: Rodent Models of Ischemic Stroke and Subarachnoid Hemorrhage

Por Sheng, Huaxin, Spasojevic, Ivan, Tse, Hubert M., Jung, Jin Yong, Hong, Jun, Zhang, Zhiquan, Piganelli, Jon D., Batinic-Haberle, Ines, Warner, David S.
Publicado em 2011

A novel redox-active metalloporphyrin reduces reactive oxygen species and inflammatory markers but does not improve marginal mass engraftment in a murine donation after circulatory...

Por Bruni, Antonio, Pepper, Andrew R., Gala-Lopez, Boris, Pawlick, Rena, Abualhassan, Nasser, Crapo, James D., Piganelli, Jon D., Shapiro, A. M. James
Publicado no Islets (2016)

Antioxidant Levels Represent a Major Determinant in the Regenerative Capacity of Muscle Stem Cells

Por Urish, Kenneth L., Vella, Joseph B., Okada, Masaho, Deasy, Bridget M., Tobita, Kimimasa, Keller, Bradley B., Cao, Baohong, Piganelli, Jon D., Huard, Johnny
Publicado em 2009

Design of Mn porphyrins for treating oxidative stress injuries and their redox-based regulation of cellular transcriptional activities

Por Batinic-Haberle, Ines, Spasojevic, Ivan, Tse, Hubert M., Tovmasyan, Artak, Rajic, Zrinka, St. Clair, Daret K., Vujaskovic, Zeljko, Dewhirst, Mark W., Piganelli, Jon D.
Publicado em 2010

Mn Porphyrin Regulation of Aerobic Glycolysis: Implications on the Activation of Diabetogenic Immune Cells

Por Delmastro-Greenwood, Meghan M., Votyakova, Tatyana, Goetzman, Eric, Marre, Meghan L., Previte, Dana M., Tovmasyan, Artak, Batinic-Haberle, Ines, Trucco, Massimo M., Piganelli, Jon D.
Publicado em 2013

Superoxide Production by Macrophages and T Cells Is Critical for the Induction of Autoreactivity and Type 1 Diabetes

Por Thayer, Terri C., Delano, Matthew, Liu, Chao, Chen, Jing, Padgett, Lindsey E., Tse, Hubert M., Annamali, Mani, Piganelli, Jon D., Moldawer, Lyle L., Mathews, Clayton E.
Publicado em 2011