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Design of Mn porphyrins for treating oxidative stress injuries and their redox-based regulation of cellular transcriptional activities

The most efficacious Mn(III) porphyrinic (MnPs) scavengers of reactive species have positive charges close to the Mn site, whereby they afford thermodynamic and electrostatic facilitation for the reaction with negatively charged species such as [Formula: see text] and ONOO(−). Those are Mn(III) meso...

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Detalhes bibliográficos
Main Authors: Batinic-Haberle, Ines, Spasojevic, Ivan, Tse, Hubert M., Tovmasyan, Artak, Rajic, Zrinka, St. Clair, Daret K., Vujaskovic, Zeljko, Dewhirst, Mark W., Piganelli, Jon D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3022969/
https://ncbi.nlm.nih.gov/pubmed/20473774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00726-010-0603-6
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