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β cell ER stress and the implications for immunogenicity in type 1 diabetes
Type 1 diabetes (T1D) is a chronic autoimmune disease characterized by hyperglycemia due to progressive immune-mediated destruction of insulin-producing pancreatic islet β cells. Although many elegant studies have identified β cell autoantigens that are targeted by the autoimmune response, the mecha...
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Publicado no: | Front Cell Dev Biol |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Frontiers Media S.A.
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4621612/ https://ncbi.nlm.nih.gov/pubmed/26579520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2015.00067 |
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