Wood Smoke Exposure and Gene Promoter Methylation Are Associated with Increased Risk for COPD in Smokers

Por Sood, Akshay, Petersen, Hans, Blanchette, Christopher M., Meek, Paula, Picchi, Maria A., Belinsky, Steven A., Tesfaigzi, Yohannes
Publicado em 2010

Methylated Genes in Sputum Among Older Smokers With Asthma

Por Sood, Akshay, Petersen, Hans, Blanchette, Christopher M., Meek, Paula, Picchi, Maria A., Belinsky, Steven A., Tesfaigzi, Yohannes
Publicado em 2012

MiR-196b is epigenetically silenced during the pre-malignant stage of lung carcinogenesis

Por Tellez, Carmen S., Juri, Daniel E., Do, Kieu, Picchi, Maria A., Wang, Teresa, Liu, Gang, Spira, Avrum, Belinsky, Steven A.
Publicado no Cancer Res (2016)

Difference in airflow obstruction between Hispanic and non-Hispanic white female smokers

Por Sood, Akshay, Stidley, Christine A., Picchi, Maria A., Celedón, Juan C., Gilliland, P.H. Frank, Crowell, Richard E., Belinsky, Steven A., Tesfaigzi, Yohannes
Publicado em 2008

Epigenetic Repression of CCDC37 and MAP1B Links Chronic Obstructive Pulmonary Disease to Lung Cancer

Por Tessema, Mathewos, Yingling, Christin M., Picchi, Maria A., Wu, Guodong, Liu, Yushi, Weissfeld, Joel L., Siegfried, Jill M., Tesfaigzi, Yohannes, Belinsky, Steven A.
Publicado no J Thorac Oncol (2015)

Multi-Vitamins, Folate, and Green Vegetables Protect Against Gene Promoter Methylation in the Aerodigestive Tract of Smokers

Por Stidley, Christine A., Picchi, Maria A., Leng, Shuguang, Willink, Randy, Crowell, Richard E., Flores, Kristina G., Kang, Huining, Byers, Tim, Gilliland, Frank D., Belinsky, Steven A.
Publicado em 2010

Sex-specific association of sequence variants in CBS and MTRR with risk for promoter hypermethylation in the lung epithelium of smokers

Por Flores, Kristina G., Stidley, Christine A., Mackey, Amanda J., Picchi, Maria A., Stabler, Sally P., Siegfried, Jill M., Byers, Tim, Berwick, Marianne, Belinsky, Steven A., Leng, Shuguang
Publicado em 2012

GATA2 is epigenetically repressed in human and mouse lung tumors and is not requisite for survival of KRAS mutant lung cancer

Por Tessema, Mathewos, Yingling, Christin M., Snider, Amanda M., Do, Kieu, Juri, Daniel E., Picchi, Maria A., Zhang, Xiequn, Liu, Yushi, Leng, Shuguang, Tellez, Carmen S., Belinsky, Steven A.
Publicado em 2014

Haplotypes of DNMT1 and DNMT3B are associated with mutagen sensitivity induced by benzo[a]pyrene diol epoxide among smokers

Por Leng, Shuguang, Stidley, Christine A., Bernauer, Amanda M., Picchi, Maria A., Sheng, Xin, Frasco, Melissa A., Van Den Berg, David, Gilliland, Frank D., Crowell, Richard E., Belinsky, Steven A.
Publicado em 2008

Discovery of common SNPs in the miR-205/200 family-regulated epithelial to mesenchymal transition pathway and their association with risk for non-small cell lung cancer

Por Leng, Shuguang, Bernauer, Amanda M, Zhai, Rihong, Tellez, Carmen S, Su, Li, Burki, Elizabeth A, Picchi, Maria A, Stidley, Christine A, Crowell, Richard E, Christiani, David C, Belinsky, Steven A
Publicado em 2011

Radon Exposure, IL-6 Promoter Variants, and Lung Squamous Cell Carcinoma in Former Uranium Miners

Por Leng, Shuguang, Thomas, Cynthia L., Snider, Amanda M., Picchi, Maria A., Chen, Wenshu, Willis, Derall G., Carr, Teara G., Krzeminski, Jacek, Desai, Dhimant, Shantu, Amin, Lin, Yong, Jacobson, Marty R., Belinsky, Steven A.
Publicado no Environ Health Perspect (2015)

A prospective and retrospective analysis of smoking behavior changes in ever smokers with high risk for lung cancer from New Mexico and Pennsylvania

Por Leng, Shuguang, Weissfeld, Joel L, Picchi, Maria A, Styn, Mindi A, Claus, Eric D, Clark, Vincent P, Wu, Guodong, Thomas, Cynthia L, Gilliland, Frank D, Yuan, Jianmin, Siegfried, Jill M, Belinsky, Steven A
Publicado no Int J Mol Epidemiol Genet (2016)

Double-strand break damage and associated DNA repair genes predispose smokers to gene methylation

Por Leng, Shuguang, Stidley, Christine A., Willink, Randy, Bernauer, Amanda, Do, Kieu, Picchi, Maria A., Sheng, Xin, Frasco, Melissa, A., Berg, David Van Den, Gilliland, Frank D., Zima, Christopher, Crowell, Richard E., Belinsky, Steven A.
Publicado em 2008

Native American Ancestry Affects the Risk for Gene Methylation in the Lungs of Hispanic Smokers from New Mexico

Por Leng, Shuguang, Liu, Yushi, Thomas, Cynthia L., Gauderman, W. James, Picchi, Maria A., Bruse, Shannon E., Zhang, Xiequn, Flores, Kristina G., Van Den Berg, David, Stidley, Christine A., Gilliland, Frank D., Belinsky, Steven A.
Publicado em 2013

Combination Therapy with Vidaza and Entinostat Suppresses Tumor Growth and Reprograms the Epigenome in an Orthotopic Lung Cancer Model

Por Belinsky, Steven A., Grimes, Marcie J., Picchi, Maria A., Mitchell, Hugh D., Stidley, Chris A, Tesfaigzi, Yohannes, Channell, Meghan M., Liu, Yanbin, Casero, Robert A., Baylin, Stephen B., Reed, Mathew D., Tellez, Carmen S., March, Thomas H.
Publicado em 2011

Genetic variation in SIRT1 affects susceptibility of lung squamous cell carcinomas in former uranium miners from the Colorado plateau

Por Leng, Shuguang, Picchi, Maria A., Liu, Yushi, Thomas, Cynthia L., Willis, Derall G., Bernauer, Amanda M., Carr, Teara G., Mabel, Padilla T., Han, Younghun, Amos, Christopher I., Lin, Yong, Stidley, Christine A., Gilliland, Frank D., Jacobson, Marty R., Belinsky, Steven A.
Publicado em 2013

Defining a Gene Promoter Methylation Signature in Sputum for Lung Cancer Risk Assessment

Por Leng, Shuguang, Do, Kieu, Yingling, Christin M., Picchi, Maria A., Wolf, Holly J., Kennedy, Timothy C., Feser, William J., Baron, Anna E., Franklin, Wilbur A., Brock, Malcolm V., Herman, James G., Baylin, Stephen B., Byers, Tim, Stidley, Christine A., Belinsky, Steven A.
Publicado em 2012

The A/G Allele of Rs16906252 Predicts for MGMT Methylation and Is Selectively Silenced in Premalignant Lesions from Smokers and in Lung Adenocarcinomas

Por Leng, Shuguang, Bernauer, Amanda M., Hong, Chibo, Do, Kieu C., Yingling, Christin M., Flores, Kristina G., Tessema, Mathewos, Tellez, Carmen S., Willink, Randall P., Burki, Elizabeth A., Picchi, Maria A., Stidley, Christine A., Prados, Michael D., Costello, Joseph F., Gilliland, Frank D., Crowell, Richard E., Belinsky, Steven A.
Publicado em 2011

Genetic Determinants for Promoter Hypermethylation in the Lungs of Smokers: A Candidate Gene-Based Study

Por Leng, Shuguang, Stidley, Christine A., Liu, Yushi, Edlund, Christopher K., Willink, Randall P., Han, Younghun, Landi, Maria Teresa, Thun, Michael, Picchi, Maria A., Bruse, Shannon E., Crowell, Richard E., Van Den Berg, David, Caporaso, Neil E., Amos, Christopher I., Siegfried, Jill M., Tesfaigzi, Yohannes, Gilliland, Frank D., Belinsky, Steven A.
Publicado em 2011

Implication of a chromosome 15q15.2 locus in regulating UBR1 and predisposing smokers to MGMT methylation in lung

Por Leng, Shuguang, Wu, Guodong, Collins, Leonard B., Thomas, Cynthia L., Tellez, Carmen S., Jauregui, Andrew R., Picchi, Maria A., Zhang, Xiequn, Juri, Daniel E., Desai, Dhimant, Amin, Shantu G., Crowell, Richard E., Stidley, Christine A., Liu, Yushi, Swenberg, James A., Lin, Yong, Wathelet, Marc G., Gilliland, Frank D., Belinsky, Steven A.
Publicado no Cancer Res (2015)