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MiR-196b is epigenetically silenced during the pre-malignant stage of lung carcinogenesis

MicroRNA silencing by promoter hypermethylation may represent a mechanism by which lung cancer develops and progresses, but the microRNAs involved during malignant transformation are unknown. We previously established a model of pre-malignant lung cancer wherein we treated human bronchial epithelial...

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Détails bibliographiques
Publié dans:Cancer Res
Auteurs principaux: Tellez, Carmen S., Juri, Daniel E., Do, Kieu, Picchi, Maria A., Wang, Teresa, Liu, Gang, Spira, Avrum, Belinsky, Steven A.
Format: Artigo
Langue:Inglês
Publié: 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987256/
https://ncbi.nlm.nih.gov/pubmed/27302168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-3367
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