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Regulation of UGT2A1 by miR-196a-5p and miR-196b-5p

UDP-glucuronosyltransferase (UGT) 2A1 is an important enzyme in the detoxification of polycyclic aromatic hydrocarbons found in cigarette smoke. This enzyme is expressed in aerodigestive tract tissues including lung as both its wild-type and exon 4-deleted splice variant isoforms, with the latter ac...

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Pubblicato in:J Pharmacol Exp Ther
Autori principali: Sutliff, Aimee K., Watson, Christy J. W., Chen, Gang, Lazarus, Philip
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Pharmacology and Experimental Therapeutics 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6439457/
https://ncbi.nlm.nih.gov/pubmed/30850392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.118.255935
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