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Regulation of UGT2A1 by miR-196a-5p and miR-196b-5p

UDP-glucuronosyltransferase (UGT) 2A1 is an important enzyme in the detoxification of polycyclic aromatic hydrocarbons found in cigarette smoke. This enzyme is expressed in aerodigestive tract tissues including lung as both its wild-type and exon 4-deleted splice variant isoforms, with the latter ac...

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Библиографические подробности
Опубликовано в: :J Pharmacol Exp Ther
Главные авторы: Sutliff, Aimee K., Watson, Christy J. W., Chen, Gang, Lazarus, Philip
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Pharmacology and Experimental Therapeutics 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6439457/
https://ncbi.nlm.nih.gov/pubmed/30850392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.118.255935
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