Epigenetic silencing of miR-137 contributes to early colorectal carcinogenesis by impaired Aurora-A inhibition

MicorRNA-137 is silenced in human colorectal cancer tissues and colon polyps. Our study showed that the decreased expression of miR-137 is significantly different in various types of polyp which maintain different potentials to lead to CRC development. The expression of miR-137 gradually decreases d...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Huang, Yu-Chuan, Lee, Chung-Ta, Lee, Jenq-Chang, Liu, Yao-Wen, Chen, Ying-Jen, Tseng, Joseph T., Kang, Jui-Wen, Sheu, Bor-Shyang, Lin, Bo-Wen, Hung, Liang-Yi
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2016
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363554/
https://ncbi.nlm.nih.gov/pubmed/27764771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12719
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