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Epigenetic silencing of LPP/miR-28 in multiple myeloma

AIMS: miR-28-5- is a tumour suppressor microRNA implicated in cancers. As a CpG island is absent in miR-28-5- but present in its host gene, LPP (LIM domain containing preferred translocation partner in lipoma), we hypothesized that miR-28-5p is epigenetically silenced by promoter DNA methylation of...

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Detalhes bibliográficos
Publicado no:J Clin Pathol
Main Authors: Li, Zhenhai, Wong, Kwan Yeung, Chan, Godfrey Chi-fung, Chim, Chor Sang
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5868533/
https://ncbi.nlm.nih.gov/pubmed/28775176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jclinpath-2017-204501
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