Epigenetic silencing of a long non-coding RNA KIAA0495 in multiple myeloma

In multiple myeloma, a long non-coding RNA, KIAA0495 (alias PDAM/TP73-AS1), had been found progressively downregulated from normal plasma cell to benign monoclonal gammopathy of undetermined significance to symptomatic myeloma. Herein, by methylation-specific PCR, the putative KIAA0495 promoter was...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Wong, Kwan Yeung, Li, Zhenhai, Zhang, Xiaoqin, Leung, Gilberto Ka Kit, Chan, Godfrey Chi-fung, Chim, Chor Sang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583761/
https://ncbi.nlm.nih.gov/pubmed/26410378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0444-8
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