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High applicability of ASO-RQPCR for detection of minimal residual disease in multiple myeloma by entirely patient-specific primers/probes

Allele-specific oligonucleotide real-time quantitative PCR (ASO-RQPCR) is a standardized technique for detection and monitoring of minimal residual disease (MRD) in acute lymphoblastic leukemia (ALL) but not multiple myeloma (MM) due to a low applicability inherent with presence of somatic hypermuta...

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Bibliographic Details
Published in:J Hematol Oncol
Main Authors: Bai, Yinlei, Wong, Kwan Yeung, Fung, Tsz Kin, Chim, Chor Sang
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5057274/
https://ncbi.nlm.nih.gov/pubmed/27724958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-016-0336-4
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