Epigenetic silencing of long non-coding RNA BM742401 in multiple myeloma: impact on prognosis and myeloma dissemination

BACKGROUND: Long non-coding RNA (lncRNA) BM742401 is a tumor suppressor in gastric cancer and chronic lymphocytic leukemia. As the promoter and coding region of BM742401 are fully embedded in a CpG island, we hypothesized that BM742401 is a tumor suppressor lncRNA epigenetically silenced by promoter...

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Veröffentlicht in:Cancer Cell Int
Hauptverfasser: Li, Zhenhai, Kumar, Shaji, Jin, Dong-Yan, Calin, George A., Chng, Wee-Joo, Siu, Kam-Leung, Poon, Ming-Wai, Chim, Chor Sang
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7446116/
https://ncbi.nlm.nih.gov/pubmed/32855620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-020-01504-4
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