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Epigenetic silencing of miR-340-5p in multiple myeloma: mechanisms and prognostic impact
BACKGROUND: miR-340-5p, localized to 5q35, is a tumor suppressor miRNA implicated in multiple cancers. As a CpG island is present at the putative promoter region of its host gene, RNF130, we hypothesized that the intronic miR-340-5p is a tumor suppressor miRNA epigenetically silenced by promoter DNA...
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| 出版年: | Clin Epigenetics |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6505104/ https://ncbi.nlm.nih.gov/pubmed/31064412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-019-0669-2 |
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