Epigenetic silencing of tumor suppressor long non-coding RNA BM742401 in chronic lymphocytic leukemia

BM742401 is a tumor suppressor lncRNA downregulated in gastric cancer. As the promoter region and the entire transcript are embedded in a CpG island, we postulated that BM742401 is a tumor suppressor lncRNA inactivated by DNA methylation in chronic lymphocytic leukemia (CLL). The promoter of BM74240...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Wang, Lu Qian, Wong, Kwan Yeung, Li, Zhen Hai, Chim, Chor Sang
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5347700/
https://ncbi.nlm.nih.gov/pubmed/27689399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12252
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