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Radon Exposure, IL-6 Promoter Variants, and Lung Squamous Cell Carcinoma in Former Uranium Miners

BACKGROUND: High radon exposure is a risk factor for squamous cell carcinoma, a major lung cancer histology observed in former uranium miners. Radon exposure can cause oxidative stress, leading to pulmonary inflammation. Interleukin-6 (IL-6) is a pro-carcinogenic inflammatory cytokine that plays a p...

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Detalhes bibliográficos
Publicado no:Environ Health Perspect
Main Authors: Leng, Shuguang, Thomas, Cynthia L., Snider, Amanda M., Picchi, Maria A., Chen, Wenshu, Willis, Derall G., Carr, Teara G., Krzeminski, Jacek, Desai, Dhimant, Shantu, Amin, Lin, Yong, Jacobson, Marty R., Belinsky, Steven A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Institute of Environmental Health Sciences 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829998/
https://ncbi.nlm.nih.gov/pubmed/26372664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1409437
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