Unravelling the rate of action of hits in the Leishmania donovani box using standard drugs amphotericin B and miltefosine

par Tegazzini, Diana, Cantizani, Juan, Peña, Imanol, Martín, Julio, Coterón, Jose M.
Publié dans PLoS Negl Trop Dis (2017)

Importance of secondary screening with clinical isolates for anti-leishmania drug discovery

par Hefnawy, Aya, Cantizani, Juan, Peña, Imanol, Manzano, Pilar, Rijal, Suman, Dujardin, Jean-Claude, De Muylder, Geraldine, Martin, Julio
Publié dans Sci Rep (2018)

Automated High-Content Assay for Compounds Selectively Toxic to Trypanosoma cruzi in a Myoblastic Cell Line

par Alonso-Padilla, Julio, Cotillo, Ignacio, Presa, Jesús L., Cantizani, Juan, Peña, Imanol, Bardera, Ana I., Martín, Jose J., Rodriguez, Ana
Publié dans PLoS Negl Trop Dis (2015)

A Replicative In Vitro Assay for Drug Discovery against Leishmania donovani

par Tegazzini, Diana, Díaz, Rosario, Aguilar, Fernando, Peña, Imanol, Presa, Jesús L., Yardley, Vanessa, Martin, Julio J., Coteron, Jose M., Croft, Simon L., Cantizani, Juan
Publié dans Antimicrob Agents Chemother (2016)

Complex Interplay between Sphingolipid and Sterol Metabolism Revealed by Perturbations to the Leishmania Metabolome Caused by Miltefosine

par Armitage, Emily G., Alqaisi, Amjed Q. I., Godzien, Joanna, Peña, Imanol, Mbekeani, Alison J., Alonso-Herranz, Vanesa, López-Gonzálvez, Ángeles, Martín, Julio, Gabarro, Raquel, Denny, Paul W., Barrett, Michael P., Barbas, Coral
Publié dans Antimicrob Agents Chemother (2018)

New Compound Sets Identified from High Throughput Phenotypic Screening Against Three Kinetoplastid Parasites: An Open Resource

par Peña, Imanol, Pilar Manzano, M., Cantizani, Juan, Kessler, Albane, Alonso-Padilla, Julio, Bardera, Ana I., Alvarez, Emilio, Colmenarejo, Gonzalo, Cotillo, Ignacio, Roquero, Irene, de Dios-Anton, Francisco, Barroso, Vanessa, Rodriguez, Ana, Gray, David W., Navarro, Miguel, Kumar, Vinod, Sherstnev, Alexander, Drewry, David H., Brown, James R., Fiandor, Jose M., Julio Martin, J.
Publié dans Sci Rep (2015)

Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition

par Wyllie, Susan, Brand, Stephen, Thomas, Michael, De Rycker, Manu, Chung, Chun-wa, Pena, Imanol, Bingham, Ryan P., Bueren-Calabuig, Juan A., Cantizani, Juan, Cebrian, David, Craggs, Peter D., Ferguson, Liam, Goswami, Panchali, Hobrath, Judith, Howe, Jonathan, Jeacock, Laura, Ko, Eun-Jung, Korczynska, Justyna, MacLean, Lorna, Manthri, Sujatha, Martinez, Maria S., Mata-Cantero, Lydia, Moniz, Sonia, Nühs, Andrea, Osuna-Cabello, Maria, Pinto, Erika, Riley, Jennifer, Robinson, Sharon, Rowland, Paul, Simeons, Frederick R. C., Shishikura, Yoko, Spinks, Daniel, Stojanovski, Laste, Thomas, John, Thompson, Stephen, Viayna Gaza, Elisabet, Wall, Richard J., Zuccotto, Fabio, Horn, David, Ferguson, Michael A. J., Fairlamb, Alan H., Fiandor, Jose M., Martin, Julio, Gray, David W., Miles, Timothy J., Gilbert, Ian H., Read, Kevin D., Marco, Maria, Wyatt, Paul G.
Publié dans Proc Natl Acad Sci U S A (2019)

Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis

par Thomas, Michael G., De Rycker, Manu, Ajakane, Myriam, Albrecht, Sébastian, Álvarez-Pedraglio, Ana Isabel, Boesche, Markus, Brand, Stephen, Campbell, Lorna, Cantizani-Perez, Juan, Cleghorn, Laura A.T., Copley, Royston C.B., Crouch, Sabrinia D., Daugan, Alain, Drewes, Gerard, Ferrer, Santiago, Ghidelli-Disse, Sonja, Gonzalez, Silvia, Gresham, Stephanie L., Hill, Alan P., Hindley, Sean J., Lowe, Rhiannon M., MacKenzie, Claire J., MacLean, Lorna, Manthri, Sujatha, Martin, Franck, Miguel-Siles, Juan, Nguyen, Van Loc, Norval, Suzanne, Osuna-Cabello, Maria, Woodland, Andrew, Patterson, Stephen, Pena, Imanol, Quesada-Campos, Maria Teresa, Reid, Iain H., Revill, Charlotte, Riley, Jennifer, Ruiz-Gomez, Jose Ramon, Shishikura, Yoko, Simeons, Frederick R.C., Smith, Alasdair, Smith, Victoria C., Spinks, Daniel, Stojanovski, Laste, Thomas, John, Thompson, Stephen, Underwood, Tim, Gray, David W., Fiandor, Jose M., Gilbert, Ian H., Wyatt, Paul G., Read, Kevin D., Miles, Timothy J.
Publié dans J Med Chem (2018)