Caspofungin Uptake Is Mediated by a High-Affinity Transporter in Candida albicans

por Paderu, Padmaja, Park, Steven, Perlin, David S.
Publicado 2004

Enfumafungin Derivative MK-3118 Shows Increased In Vitro Potency against Clinical Echinocandin-Resistant Candida Species and Aspergillus Species Isolates

por Jiménez-Ortigosa, Cristina, Paderu, Padmaja, Motyl, Mary R., Perlin, David S.
Publicado 2014

Molecular Evaluation of the Plasma Membrane Proton Pump from Aspergillus fumigatus

por Burghoorn, Henriette P., Soteropoulos, Patricia, Paderu, Padmaja, Kashiwazaki, Ryota, Perlin, David S.
Publicado 2002

Expression Turnover Profiling To Monitor the Antifungal Activities of Amphotericin B, Voriconazole, and Micafungin against Aspergillus fumigatus

por Zhao, Yanan, Paderu, Padmaja, Park, Steven, Dukhan, Aleksandra, Senter, Meredith, Perlin, David S.
Publicado 2012

Serum Differentially Alters the Antifungal Properties of Echinocandin Drugs

por Paderu, Padmaja, Garcia-Effron, Guillermo, Balashov, Sergey, Delmas, Guillaume, Park, Steven, Perlin, David S.
Publicado 2007

Efficacy of Oral Cochleate-Amphotericin B in a Mouse Model of Systemic Candidiasis

por Santangelo, Rosaria, Paderu, Padmaja, Delmas, Guillaume, Chen, Zi-Wei, Mannino, Raphael, Zarif, Leila, Perlin, David S.
Publicado 2000

Molecular Characterization of the Plasma Membrane H(+)-ATPase, an Antifungal Target in Cryptococcus neoformans

por Soteropoulos, Patricia, Vaz, Tanya, Santangelo, Rosaria, Paderu, Padmaja, Huang, David Y., Tamás, Markus J., Perlin, David S.
Publicado 2000

Lipid Flippase Subunit Cdc50 Mediates Drug Resistance and Virulence in Cryptococcus neoformans

por Huang, Wei, Liao, Guojian, Baker, Gregory M., Wang, Yina, Lau, Richard, Paderu, Padmaja, Perlin, David S., Xue, Chaoyang
Publicado en mBio (2016)

Differential Regulation of Echinocandin Targets Fks1 and Fks2 in Candida glabrata by the Post-Transcriptional Regulator Ssd1

por Healey, Kelley R., Paderu, Padmaja, Hou, Xin, Jimenez Ortigosa, Cristina, Bagley, Nicole, Patel, Biren, Zhao, Yanan, Perlin, David S.
Publicado en J Fungi (Basel) (2020)

Significantly Improved Pharmacokinetics Enhances In Vivo Efficacy of APX001 against Echinocandin- and Multidrug-Resistant Candida Isolates in a Mouse Model of Invasive Candidiasis

por Zhao, Yanan, Lee, Min Hee, Paderu, Padmaja, Lee, Annie, Jimenez-Ortigosa, Cristina, Park, Steven, Mansbach, Robert S., Shaw, Karen Joy, Perlin, David S.
Publicado en Antimicrob Agents Chemother (2018)

Trehalose-6-Phosphate Phosphatase is required for cell wall integrity and fungal virulence but not trehalose biosynthesis in the human fungal pathogen Aspergillus fumigatus

por Puttikamonkul, Srisombat, Willger, Sven D., Grahl, Nora, Perfect, John R., Movahed, Navid, Bothner, Brian, Park, Steven, Paderu, Padmaja, Perlin, David S., Cramer, Robert A.
Publicado 2010

Novel FKS1 and FKS2 modifications in a high-level echinocandin resistant clinical isolate of Candida glabrata

por Hou, Xin, Healey, Kelley R., Shor, Erika, Kordalewska, Milena, Ortigosa, Cristina Jiménez, Paderu, Padmaja, Xiao, Meng, Wang, He, Zhao, Ying, Lin, Li-Yan, Zhang, Yan-Hai, Li, Yong-Zhe, Xu, Ying-Chun, Perlin, David S., Zhao, Yanan
Publicado en Emerg Microbes Infect (2019)